Genome-wide analysis of transcription factor binding sites and their characteristic DNA structures

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• 作者：Zhiming Dai ; Dongliang Guo ; Xianhua Dai ; Yuanyan Xiong
• 刊名：BMC Genomics
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：16
• 期：3-supp
• 全文大小：1,692 KB
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• 作者单位：Zhiming Dai (1)
  Dongliang Guo (1)
  Xianhua Dai (1)
  Yuanyan Xiong (2) (3)
  
  1. Department of Electronics and Communication Engineering, School of Information Science and Technology, Sun Yat-Sen University, Guangzhou, 510006, China
  2. State Key laboratory for Biocontrol, Sun Yat-Sen University, Guangzhou, 510275, China
  3. SYSU-CMU Shunde International Joint Research Institute, Shunde, China
  
• 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
• 出版者：BioMed Central
• ISSN：1471-2164

文摘

Background Transcription factors (TF) regulate gene expression by binding DNA regulatory regions. Transcription factor binding sites (TFBSs) are conserved not only in primary DNA sequences but also in DNA structures. However, the global relationship between TFs and their preferred DNA structures remains to be elucidated.