Lipopolysaccharide challenge significantly influences lipid metabolism and proteome of white adipose tissue in growing pigs
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- 作者：Jun Guo ; Zhiqing Liu ; Hailin Sun ; Yanping Huang…
- 关键词：Acute inflammation ; Lipid metabolism ; Proteome ; White adipose tissue ; Pig
- 刊名：Lipids in Health and Disease
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：14
- 期：1
- 全文大小：1,117 KB
- 刊物主题：Lipidology; Medical Biochemistry;
- 出版者：BioMed Central
- ISSN：1476-511X
文摘
Background White adipose tissue is recognized as a highly active organ, which is closely related to a large number of physiological and metabolic processes besides storing triglycerides. However, little is known regarding the response of adipose tissue to acute inflammation. Therefore, in this study we employed growing pigs to investigate the changes of lipid metabolism and proteome in white adipose tissue after lipopolysaccharide (LPS) stimulation as a model for bacterial infection.