The movement and deposition of PM2.5 in the upper respiratory tract for the patients with heart failure: an elementary CFD study

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• 作者：Tiantian Zhang ; Bin Gao ; Zhixiang Zhou ; Yu Chang
• 关键词：PM2.5 ; Heart failure ; Aerodynamics ; Particle deposition ; Wall shear stress
• 刊名：BioMedical Engineering OnLine
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：15
• 期：2-supp
• 全文大小：1891KB
• 刊物类别：Engineering
• 刊物主题：Biomedical Engineering; Biomaterials; Biotechnology; Biomedical Engineering/Biotechnology;
• 出版者：BioMed Central
• ISSN：1475-925X
• 卷排序：15

文摘

BackgroundPM2.5 is an important factor to affect the patients with respiratory and cardiovascular diseases. Clinical studies have found that the morbidity and mortality of patients with heart failure (HF) have a close relationship with the movement and deposition state of PM2.5. One reason is that the breathing pattern of patients with HF has obvious difference with healthy people, however the effect caused by these differences on the distribution regularity of PM2.5 in the respiratory tract is still unclear. Hence, a computational fluid dynamics simulation was conducted to clarify the aerodynamic effect of breathing pattern of patients with HF on respiratory system.