A gangliocytic patially glandular paraganglioma with lymph node metastasis

详细信息    查看全文

• 作者：Huijuan Shi (8)
  Ju Han (8)
  Ni Liu (8)
  Ziyin Ye (8)
  Zhixun Li (8)
  Zhi Li (8)
  Tingsheng Peng (8)
  
  8. Department of Pathology ; the First Affiliated Hospital of Sun Yat-sen University ; 58 ; Zhongshan Road II ; Guangzhou ; 510080 ; P. R. China
  
• 关键词：Gangliocytic paraganglioma ; Glandular component ; Lymph node metastasis ; Duodenum
• 刊名：Diagnostic Pathology
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：9
• 期：1
• 全文大小：763 KB
• 参考文献：1. Dahl, EV, Waugh, JM, Dahlin, DC (1957) Gastrointestinal ganglioneuromas; brief review with report of a duodenal ganglioneuroma. Am J Pathol 33: pp. 953-965
  2. Kepes, JJ, Zacharias, DL (1971) Gangliocytic paragangliomas of the duodenum. A report of two cases with light and electron microscopic examination. Cancer 27: pp. 61-67 CrossRef
  3. Nu帽o-Guzm谩na, CM, Arr贸niz-J谩ureguia, J, Alvarez-L贸pezb, F, Corona, JL, Cerda-Camacho, F, Rostro, R, Guti茅rrez-Manjarrez, JI (2012) Obstructing gangliocytic paraganglioma in the third portion of the duodenum. Gastroenterol 6: pp. 489-495
  4. van Eeden, S, Offerhaus, GJ, Peterse, HL, Dingemans, KP, Blaauwgeers, HL (2000) Gangliocytic paraganglioma of the appendix. Histopathology 36: pp. 47-49 CrossRef
  5. Jinchen, H, Jitao, W, Cai, L, Jiang, L, Lang, Z, Qu, G, Liu, H, Yao, W, Yu, G (2013) Retroperitoneal composite pheochromocytoma-ganglioneuroma: a case report and review of literature. Diagn Pathol 8: pp. 63-67 CrossRef
  6. Zhao, L, Luo, J, Zhang, H, Da, J (2012) Pigmented paraganglioma of the kidney: a case report. Diagn Pathol 7: pp. 77-81 CrossRef
  7. B眉chler, M, Malfertheiner, P, Baczako, K, Krautzberger, W, Beger, HG (1985) A metastatic endocrine-neurogenic tumor of the ampulla of Vater with multiple endocrine immunoreaction鈥搈alignant paraganglioma?. Digestion 31: pp. 54-59 CrossRef
  8. Inai, K, Kobuke, T, Yonehara, S, Tokuoka, S (1989) Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17-year-old boy. Cancer 63: pp. 2540-2545 CrossRef
  9. Hashimoto, S, Kawasaki, S, Matsuzawa, K, Harada, H, Makuuchi, M (1992) Gangliocytic paraganglioma of the papilla of Vater with regional lymph node metastasis. Am J Gastroenterol 87: pp. 1216-1218
  10. Dookhan, DB, Miettinen, M, Finkel, G, Gibas, Z (1993) Recurrent duodenal gangliocytic paraganglioma with lymph node metastases. Histopathology 22: pp. 399-401 CrossRef
  11. Sundararajan, V, Robinson-Smith, TM, Lowy, AM (2003) Duodenal gangliocytic paraganglioma with lymph node metastasis: a case report and review of the literature. Arch Pathol Lab Med 127: pp. e139-e141
  12. Bucher, P, Mathe, Z, B眉hler, L, Chilcott, M, Gervaz, P, Egger, JF, Morel, P (2004) Paraganglioma of the ampulla of Vater: a potentially malignant neoplasm. Scand J Gastroenterol 39: pp. 291-295 CrossRef
  13. Wong, A, Miller, AR, Metter, J, Thomas, CR (2005) Locally advanced duodenal gangliocytic paraganglioma treated with adjuvant radiation therapy: case report and review of the literature. World J Surg Oncol 3: pp. 15 CrossRef
  14. Witkiewicz, A, Galler, A, Yeo, CJ, Gross, SD (2007) Gangliocytic paraganglioma: case report and review of the literature. J Gastrointest Surg 11: pp. 1351-1354 CrossRef
  15. Mann, CM, Bramhall, SR, Buckels, JA, Taniere, P (2009) An unusual case of duodenal obstruction-gangliocytic paraganglioma. J Hepatobiliary Pancreat Surg 16: pp. 562-565 CrossRef
  16. Okubo, Y, Yokose, T, Tuchiya, M, Mituda, A, Wakayama, M, Hasegawa, C, Sasai, D, Nemoto, T, Shibuya, K (2010) Duodenal gangliocytic paraganglioma showing lymph node metastasis: a rare case report. Diagn Pathol 5: pp. 27 CrossRef
  17. Saito, J, Hirata, N, Furuzono, M, Nakaji, S, Inase, M, Nagano, H, Iwata, M, Tochitani, S, Fukatsu, K, Fujii, H, Ishii, E, Kataoka, J, Mikata, R, Masuya, Y, Ito, H, Ohmori, J, Wakasugi, S, Ebara, M, Hoshi, K (2010) A case of duodenal gangliocytic paraganglioma with lymph node metastasis. Nihon Shokakibyo Gakkai Zasshi 107: pp. 639-648
  18. Uchida, D, Ogawa, T, Ueki, T, Kominami, Y, Numata, N, Matsusita, H, Morimoto, Y, Nakarai, A, Ota, S, Nanba, S, Takada, S, Iwado, S, Kurome, M, Ohe, H, Okamoto, R, Uematsu, S, Nakagawa, M, Ishida, K, Araki, Y, Mizuno, M (2010) A case of gangliocytic paraganglioma with lymphoid metastasis. Nihon Shokakibyo Gakkai Zasshi 107: pp. 1456-1465
  19. Ogata, S, Horio, T, Sugiura, Y, Aiko, S, Aida, S (2011) Duodenal gangliocytic paraganglioma with regional lymph node metastasis and a glandular component. Pathol Int 61: pp. 104-107 CrossRef
  20. Barret, M, Rahmi, G, Duong van Huyen, JP, Landi, B, Cellier, C, Berger, A (2012) Duodenal gangliocytic paraganglioma with lymph node metastasis and an 8-year follow-up: a case report. Eur J Gastroenterol Hepatol 24: pp. 90-94 CrossRef
  21. Anders, KH, Glasgow, BJ, Lewin, KJ (1987) Gangliocytic paraganglioma associated with duodenal adenocarcinoma. Case report with immunohistochemical evaluation. Arch Pathol Lab Med 111: pp. 49-52
  
• 刊物主题：Pathology;
• 出版者：BioMed Central
• ISSN：1746-1596

文摘

Gangliocytic paraganglioma (GP) is an infrequent neuroendocrine tumor usually with three elements as epithelioid cells, spindle-shaped cells and ganglion-like cells, which is generally regarded as a benign tumor. Only a few cases with lymph node metastasis have been reported. Herein, we reported a 47-year-old man of GP with distinct glandular component embedded in the spindle tumor cells in the primary tumor and the metastatic lymph nodes. The immunohistochemical profile was helpful to give the final diagnosis as gangliocytic paraganglioma. Here, we added one more GP case with regional lymph nodes metastasis. And particularly, there were small amount of distinct glandular component both in the primary tumor and the metastatic lymph nodes, which indicated that adenocarcinoma might coexist with GP. And GP should also be distinguished from carcinoid tumor, paraganglioma, ganglioneuroma, or GIST.