Influence of blood-brain barrier permeability on O-(2-18F-fluoroethyl)-L-tyrosine uptake in rat gliomas
详细信息 查看全文
- 作者：Carina Stegmayr ; Ulrike Bandelow…
- 关键词：PET ; Brain tumors ; O ; (2 ; [18F]fluoroethyl) ; L ; tyrosine (18F ; FET) ; Blood brain barrier (BBB) ; Dexamethasone
- 刊名：European Journal of Nuclear Medicine and Molecular Imaging
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：44
- 期：3
- 页码：408-416
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology;
- 出版者：Springer Berlin Heidelberg
- ISSN：1619-7089
- 卷排序：44
文摘
PurposeO-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) is an established tracer for the diagnosis of brain tumors with PET. This study investigates the influence of blood-brain barrier (BBB) permeability on 18F-FET uptake in two rat glioma models and one human xenograft model.