A dual substrate kinetic model for cytochrome P450BM3-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol
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- 作者：Chelsea Ledford ; Monica McMahon ; Ashley Whitesell ; Ghalib Khan…
- 关键词：Active site ; Aldehydes ; Benzoquinone ; Cytochrome P450 ; De ; fluorination ; 4 ; Fluorophenol
- 刊名：Biotechnology Letters
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：39
- 期：2
- 页码：311-321
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
- 出版者：Springer Netherlands
- ISSN：1573-6776
- 卷排序：39
文摘
ObjectiveTo develop a model for binding and catalysis associated with the stimulation of 4-fluorophenol (4-FP) oxidation in the presence of long chain aldehydes by the enzymatic catalyst, cytochrome P450BM3-F87G.