Assessing the burden of treatment-emergent adverse events associated with atypical antipsychotic medications

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• 作者：Pierre-Michel Llorca ; Christophe Lançon ; Ann Hartry ; T. Michelle Brown…
• 关键词：Schizophrenia ; Major depressive disorder ; Atypical antipsychotics ; Treatment ; emergent adverse events
• 刊名：BMC Psychiatry
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：489KB
• 刊物主题：Psychiatry; Psychotherapy;
• 出版者：BioMed Central
• ISSN：1471-244X
• 卷排序：17

文摘

BackgroundTreatment of schizophrenia and major depressive disorder (MDD) with atypical antipsychotics (AAPs) show improved efficacy and reduced side effect burden compared with older antipsychotic medications. However, a risk of treatment-emergent adverse events (TEAEs) remains. TEAEs are hard to quantify and perspectives on the importance of TEAEs differ across patients and between patients and physicians. The current study is a qualitative assessment that investigates TEAEs of AAPs from both patient and physician perspectives to provide better understanding of the occurrence and burden of TEAEs associated with these medications.