Steroids in bacterial meningitis: yes

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• 作者：Felix Benninger (1)
  Israel Steiner (1)
  
• 关键词：Meningitis ; Steroids ; Treatment ; Bacterial
• 刊名：Journal of Neural Transmission
• 出版年：2013
• 出版时间：February 2013
• 年：2013
• 卷：120
• 期：2
• 页码：339-342
• 全文大小：158KB
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• 作者单位：Felix Benninger (1)
  Israel Steiner (1)
  
  1. Department of Neurology, Rabin Medical Center, Campus Beilinson, Petach Tikva, Israel
  
• ISSN：1435-1463

文摘

Bacterial meningitis is an infectious condition associated with severe morbidity and mortality, even with rapid diagnosis and appropriate antibiotic therapy. Despite decrease in the rate of bacterial meningitis brought about by vaccination programs against Haemophilus influenzae type-B and Streptococcus pneumonia, the incidence of meningitis is still unacceptably high and acute treatment remains the mainstay of therapy. The infection is accompanied by intense inflammatory response, which may carry deleterious effects upon the tissue. This led to the possibility of adjuvant corticosteroid therapy, as an anti-inflammatory agent, in bacterial meningitis. The debate focuses on the rational and evidence supporting and refuting such an approach.