Wideband phase locking to modulated whisker vibration point to a temporal code for texture in the rat’s barrel cortex

详细信息    查看全文

• 作者：Tobias A. S. Ewert ; Johannes M?ller ; Andreas K. Engel…
• 关键词：Anaesthesia ; Electrophysiology ; High ; frequency vibration ; Tactile processing ; Oscillation
• 刊名：Experimental Brain Research
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：233
• 期：10
• 页码：2869-2882
• 全文大小：5,379 KB
• 参考文献：Andermann ML, Ritt J, Neimark MA, Moore CI (2004) Neural correlates of vibrissa resonance: band-pass and somatotopic representation of high-frequency stimuli. Neuron 42:451-63CrossRef PubMed
  Andres KH (1966) über die Feinstruktur der Rezeptoren in Sinushaaren. Z Zellforsch 75:339-65CrossRef PubMed
  Arabzadeh E, Petersen RS, Diamond ME (2003) Encoding of whisker vibration by rat barrel cortex neurons: implications for texture discrimination. J Neurosci 23:9146-154PubMed
  Arabzadeh E, Panzeri S, Diamond ME (2006) Deciphering the spike train of a sensory neuron: counts and temporal patterns in the rat whisker pathway. J Neurosci 26:9216-226CrossRef PubMed
  Bale MR, Davies K, Freeman OJ, Ince RAA, Petersen RS (2013) Low-dimensional sensory feature representation by trigeminal primary afferents. J Neurosci 33:12003-2012PubMed Central CrossRef PubMed
  Boloori A-R, Jenks RA, Desbordes G, Stanley GB (2010) Encoding and decoding cortical representations of tactile features in the vibrissa system. J Neurosci 30:9990-0005PubMed Central CrossRef PubMed
  Brecht M, Sakmann B (2002) Whisker maps of neuronal subclasses of the rat ventral posterior medial thalamus, identified by whole-cell voltage recording and morphological reconstruction. J Physiol 538:495-15PubMed Central CrossRef PubMed
  Bruno RM, Sakmann B (2006) Cortex is driven by weak but synchronously active thalamocortical synapses. Science 312:1622-627CrossRef PubMed
  Carvell GE, Simons DJ (1990) Biometric analyses of vibrissal tactile discrimination in the rat. J Neurosci 10:2638-648PubMed
  Castro-Alamancos MA (2002) Different temporal processing of sensory inputs in the rat thalamus during quiescent and information processing states in vivo. J Physiol 539:567-78PubMed Central CrossRef PubMed
  Castro-Alamancos MA (2004) Absence of rapid sensory adaptation in neocortex during information processing states. Neuron 41:455-64CrossRef PubMed
  Deschênes M, Timofeeva E, Lavallee P (2003) The relay of high-frequency sensory signals in the whisker-to-barreloid pathway. J Neurosci 23:6778-787PubMed
  Engel AK, K?nig P, Kreiter AK, Schillen TB, Singer W (1992) Temporal coding in the visual cortex: new vistas on integration in the nervous system. Trends Neurosci 15:218-26CrossRef PubMed
  Engel AK, Fries P, Singer W (2001) Dynamic predictions: oscillations and synchrony in top-down processing. Nat Rev Neurosci 2:704-16CrossRef PubMed
  Ewert TAS, Vahle-Hinc C, Engel AK (2008) High-frequency whisker vibration is encoded by phase-locked responses of neurons in the rat’s barrel cortex. J Neurosci 28:5359-368CrossRef PubMed
  Garabedian CE, Jones SR, Merzenich MM, Dale A, Moore CI (2003) Band-pass response properties of rat SI neurons. J Neurophysiol 90:1379-391CrossRef PubMed
  Gibson JM, Welker WI (1983) Quantitative studies of stimulus coding in first-order vibrissa afferents of rats. 2. Adaptation and coding of stimulus parameters. Somatosens Res 1:95-17CrossRef PubMed
  Gil Z, Connors BW, Amitai Y (1999) Efficacy of thalamocortical and intracortical synaptic connections: quanta, innervation, and reliability. Neuron 23:385-97CrossRef PubMed
  Gottschaldt KM, Vahle-Hinz C (1981) Merkel cell receptors: structure and transducer function. Science 214:183-86CrossRef PubMed
  Guic-Robles E, Valdivieso C, Guajardo G (1989) Rats can learn a roughness discrimination using only their vibrissal system. Behav Brain Res 31:285-89CrossRef PubMed
  Hamada Y, Miyashita E, Tanaka H (1999) Gamma-band oscillations in the “barrel cortex-precede rat’s exploratory whisking. Neuroscience 88:667-71CrossRef PubMed
  Hartmann MJ, Johnson NJ, Towal RB, Assad C (2003) Mechanical characteristics of rat vibrissae: resonant frequencies and damping in isolated whiskers and in the awake behaving animal. J Neurosci 23:6510-519PubMed
  Hernandez A, Zainos A, Romo R (2000) Neural correlates of sensory discrimination in the somatosensory cortex. Proc Natl Acad Sci 97:6191-196PubMed Central CrossRef PubMed
  Herrmann CS, Munk MHJ, Engel AK (2004) Cognitive functions of gamma-band activity: memory match and utilization. Trends Cogn Sci 8:347-55CrossRef PubMed
  Hipp J, Arabzadeh E, Zorkin E, Conradt J, Kayser C, Diamond ME (2006) Texture signals in whisker vibrations. J Neurophysiol 95:1792-799CrossRef PubMed
  Hollins M, Bensmaia SJ (2007) The coding of roughness. Can J Exp Psychol 61:184-95CrossRef PubMed
  Jadhav SP, Feldman DE (2010) Texture coding in the whisker system. Curr Opin Neurobiol 20:313-18CrossRef PubMed
  Jadhav SP, Wolfe J, Feldman DE (2009) Sparse temporal coding of elementary tactile features during active whisker sensation. Nat Neurosci 12:792-00CrossRef PubMed
  Jones MS, Barth DS (1997) Sensory-evoked high-frequency (γ-band) oscillating potentials in somatosensory cortex of the unanesthetized rat. Brain Res 768:167-76CrossRef PubMed
  Jones LM, Depireux DA, Simons DJ, Keller A (2004a) Robust
• 作者单位：Tobias A. S. Ewert (1) (2)
  Johannes M?ller (1)
  Andreas K. Engel (1)
  Christiane Vahle-Hinz (1)
  
  1. Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany
  2. Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Neurosciences
  Neurology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-1106

文摘

Rats probe objects with their whiskers and make decisions about sizes, shapes, textures and distances within a few tens of milliseconds. This perceptual analysis requires the processing of tactile high-frequency object components reflecting surface roughness. We have shown that neurons in the barrel cortex of rats encode high-frequency sinusoidal vibrations of whiskers for sustained periods when presented with constant amplitudes and frequencies. In a natural situation, however, stimulus parameters change rapidly when whiskers are brushing across objects. In this study, we therefore analysed cortical responses to vibratory movements of single whiskers with rapidly changing amplitudes and frequencies. The results show that different neural codes are employed for a processing of stimulus parameters. The frequency of whisker vibration is encoded by the temporal pattern of spike discharges, i.e., the phase-locked responses of barrel cortex neurons. In addition, oscillatory gamma band activity was induced during high-frequency stimulation. The pivotal descriptor of the amplitude of whisker displacement, the velocity, is reflected in the rate of spike discharges. While phase-locked discharges occurred over the entire range of frequencies tested (10-00 Hz), the discharge rate increased with stimulus velocity only up to about 60 μm/ms, saturating at a mean rate of ~117 spikes/s. In addition, the results show that whisker movements of more than 500 Hz bandwidth may be encoded by phase-locked responses of small groups of cortical neurons. Thus, even single whiskers may transmit information about wide ranges of textural components owing to their set of different types of hair follicle mechanoreceptors. Keywords Anaesthesia Electrophysiology High-frequency vibration Tactile processing Oscillation