Detection of positive and negative ions from a flowing atmospheric pressure afterglow using a mattauch-herzog mass spectrograph equipped with a faraday-strip array detector

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• 作者：Gregory D. Schilling (1)
  Jacob T. Shelley (1)
  James H. Barnes (2)
  Roger P. Sperline (3)
  M. Bonner Denton (3)
  Charles J. Barinaga (4)
  David W. Koppenaal (4)
  Gary M. Hieftje (1)
  
• 刊名：Journal of The American Society for Mass Spectrometry
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：21
• 期：1
• 页码：97-103
• 全文大小：1063KB
• 参考文献：1. Andrade, F. J.; Shelley, J. T.; Wetzel, W. C.; Webb, M. R.; Gamez, G.; Ray, S. J.; Hieftje, G. M. Atmospheric Pressure Chemical Ionization Source. 1: Ionization of Compounds in the Gas Phase. / Anal. Chem. 2008, / 80, 2646-653. CrossRef
  2. Andrade, F. J.; Shelley, J. T.; Wetzel, W. C.; Webb, M. R.; Gamez, G.; Ray, S. J.; Hieftje, G. M. Atmospheric Pressure Chemical Ionization Source. 2: Desorption-Ionization for the Direct Analysis of Solid Compounds. / Anal. Chem. 2008, / 80, 2654-663. CrossRef
  3. Shelley, J. T.; Ray, S. J.; Hieftje, G. M. Laser Ablation Coupled to a Flowing Atmospheric Pressure Afterglow for Ambient Mass Spectral Imaging. / Anal. Chem. 2008, / 80, 8308-313. CrossRef
  4. Barnes, J. H.; Schilling, G. D.; Sperline, R.; Denton, M. B.; Young, E. T.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Characterization of a Focal Plane Camera Fitted to a Mattauch-Herzog Geometry Mass Spectrograph. 2: Use with an Inductively Coupled Plasma. / Anal. Chem. 2004, / 76, 2531-536. CrossRef
  5. Barnes, J. H. IV; Schilling, G. D.; Hieftje, G. M.; Sperline, R. P.; Denton, M. B.; Barinaga, C. J.; Koppenaal, D. W. Use of a Novel Array Detector for the Direct Analysis of Solid Samples by Laser Ablation Inductively Coupled Plasma Sector-Field Mass Spectrometry. / J. Am. Soc. Mass Spectrom. 2004, / 15, 769-76. CrossRef
  6. Barnes, J. H. IV; Schilling, G. D.; Sperline, R. P.; Denton, M. B.; Young, E. T.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Coupling of a Gas Chromatograph to a Simultaneous-Detection Inductively Coupled Plasma Mass Spectrograph for Speciation of Organohalide and Organometallic Compounds. / J. Anal. At. Spectrom. 2004, / 19, 751-56. CrossRef
  7. Barnes, J. H. IV; Schilling, G. D.; Stone, S. F.; Sperline, R. P.; Denton, M. B.; Young, E. T.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Simultaneous Multichannel Mass-Specific Detection for High-Performance Liquid Chromatography Using an Array Detector Sector-Field Mass Spectrometer. / Anal. Bioanal. Chem. 2004, / 380, 227-34. CrossRef
  8. Barnes, J. H. IV; Sperline, R.; Denton, M. B.; Barinaga, C. J.; Koppenaal, D.; Young, E. T.; Hieftje, G. M. Characterization of a Focal Plane Camera Fitted to a Mattauch-Herzog Geometry Mass Spectrograph. 1: Use with a Glow-Discharge Source. / Anal. Chem. 2002, / 74, 5327-332. CrossRef
  9. Schilling, G. D.; Andrade, F. J.; Barnes, J. H.; Sperline, R. P.; Denton, M. B.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Characterization of a Second-Generation Focal-Plane Camera Coupled to an Inductively Coupled Plasma Mattauch-Herzog Geometry Mass Spectrograph. / Anal. Chem. 2006, / 78, 4319-325. CrossRef
  10. Schilling, G. D.; Andrade, F. J.; Barnes, J. H., IV; Sperline, R. P.; Denton, M. B.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Continuous Simultaneous Detection in Mass Spectrometry. / Anal. Chem. 2007, / 79, 7662-668. CrossRef
  11. Andrade, F. J.; Wetzel, W. C.; Chan, G. C. Y.; Webb, M. R.; Gamez, G.; Ray, S. J.; Hieftje, G. M. A New, Versatile, Direct-Current Helium Atmospheric-Pressure Glow Discharge. / J. Anal. At. Spectrom. 2006, / 21, 1175-184. CrossRef
  12. Schilling, G. D.; Shelley, J. T.; Broekaert, J. A. C.; Sperline, R. P.; Denton, M. B.; Barinaga, C. J.; Koppenaal, D. W.; Hieftje, G. M. Use of an Ambient Ionization Flowing Atmospheric-Pressure Afterglow Source for Elemental Analysis Through Hydride Generation. / J. Anal. At. Spectrom. 2008, / 24, 34-0. CrossRef
  13. Barnes, J. H., IV; Schilling, G. D.; Denton, M. B.; Koppenaal, D. W.; Hieftje, G. M. Development and Characterization of an Electrostatic Quadrupole Extraction Lens for Mass Spectrometry. / J. Anal. At. Spectrom. 2003, / 18, 1015-018. CrossRef
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  15. Harrison, A. G. / Chemical Ionization Mass Spectrometry, 2nd ed.; CRC Press: Boca Raton, FL, 1992; p. 208.
  
• 作者单位：Gregory D. Schilling (1)
  Jacob T. Shelley (1)
  James H. Barnes (2)
  Roger P. Sperline (3)
  M. Bonner Denton (3)
  Charles J. Barinaga (4)
  David W. Koppenaal (4)
  Gary M. Hieftje (1)
  
  1. Department of Chemistry, Indiana University, 47405, Bloomington, IN, USA
  2. University Multispectral Laboratories, Ponca City, Oklahoma, USA
  3. Department of Chemistry, University of Arizona, Tucson, Arizona, USA
  4. Pacific Northwest National Laboratory, Richland, Washington, USA
  

文摘

An ambient desorption/ionization (ADI) source, known as the flowing atmospheric pressure afterglow (FAPA), has been coupled to a Mattauch-Herzog mass spectrograph (MHMS) equipped with a focal plane camera (FPC) array detector. The FAPA ionization source enables direct mass spectral analysis of solids, liquids, and gases through either positive or negative ionization modes. In either case, spectra are generally simple with dominant peaks being the molecular ions or protonated molecular ions. Use of the FAPA source with the MHMS allows the FPC detector to be characterized for the determination of molecular species, whereas previously only atomic mass spectrometry (MS) has been demonstrated. Furthermore, the FPC is shown to be sensitive to negative ions without the need to change any detector parameters. The analysis of solid, liquid, and gaseous samples through positive and negative ionization is demonstrated with detection limits (1-5 fmol/s, ?. 3-0 pg of analyte per mL of helium) surpassing those obtained with the FAPA source coupled to a time-of-flight mass analyzer.