K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar
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- 作者：Aye A. Win ; Mallika Imwong ; Myat P. Kyaw ; Charles J. Woodrow…
- 关键词：Malaria ; Plasmodium falciparum ; K13 mutation ; pfmdr1 copy number variation ; Artemisinin resistance ; Myanmar
- 刊名：Malaria Journal
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：15
- 期：1
- 全文大小：1,155 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Background Artemisinin-based combination therapy has been first-line treatment for falciparum malaria in Myanmar since 2005. The wide extent of artemisinin resistance in the Greater Mekong sub-region and the presence of mefloquine resistance at the Myanmar-Thailand border raise concerns over resistance patterns in Myanmar. The availability of molecular markers for resistance to both drugs enables assessment even in remote malaria-endemic areas.