The effect of iterative model reconstruction on coronary artery calcium quantification
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  • 作者:Bálint Szilveszter ; Hesham Elzomor…
  • 关键词:Coronary artery disease ; Computed tomography ; Iterative model reconstruction ; Coronary artery calcium scoring ; Risk stratification
  • 刊名:The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging)
  • 出版年:2016
  • 出版时间:January 2016
  • 年:2016
  • 卷:32
  • 期:1
  • 页码:153-160
  • 全文大小:592 KB
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  • 作者单位:Bálint Szilveszter (1)
    Hesham Elzomor (1)
    Mihály Károlyi (1)
    Márton Kolossváry (1)
    Rolf Raaijmakers (2)
    Kálmán Benke (1)
    Csilla Celeng (1)
    Andrea Bartykowszki (1)
    Zsolt Bagyura (1)
    Árpád Lux (1)
    Béla Merkely (1)
    Pál Maurovich-Horvat (1)

    1. MTA-SE Lendület Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Varosmajor ut, Budapest, 1122, Hungary
    2. Philips HealthTech, Veenpluis 4-6, 5684 PC, Best, The Netherlands
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Cardiology
  • 出版者:Springer Netherlands
  • ISSN:1573-0743
文摘
Coronary artery calcium (CAC) scoring with computed tomography (CT) is an established tool for quantifying calcified atherosclerotic plaque burden. Despite the widespread use of novel image reconstruction techniques in CT, the effect of iterative model reconstruction on CAC score remains unclear. We sought to assess the impact of iterative model based reconstruction (IMR) on coronary artery calcium quantification as compared to the standard filtered back projection (FBP) algorithm and hybrid iterative reconstruction (HIR). In addition, we aimed to simulate the impact of iterative reconstruction techniques on calcium scoring based risk stratification of a larger asymptomatic population. We studied 63 individuals who underwent CAC scoring. Images were reconstructed with FBP, HIR and IMR and CAC scores were measured. We estimated the cardiovascular risk reclassification rate of IMR versus HIR and FBP in a larger asymptomatic population (n = 504). The median CAC scores were 147.7 (IQR 9.6–582.9), 107.0 (IQR 5.9–526.6) and 115.1 (IQR 9.3–508.3) for FBP, HIR and IMR, respectively. The HIR and IMR resulted in lower CAC scores as compared to FBP (both p < 0.001), however there was no difference between HIR and IMR (p = 0.855). The CAC score decreased by 7.2 % in HIR and 7.3 % in IMR as compared to FBP, resulting in a risk reclassification rate of 2.4 % for both HIR and IMR. The utilization of IMR for CAC scoring reduces the measured calcium quantity. However, the CAC score based risk stratification demonstrated modest reclassification in IMR and HIR versus FBP. Keywords Coronary artery disease Computed tomography Iterative model reconstruction Coronary artery calcium scoring Risk stratification

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