The Analysis on Risk Factors and Clinical Treatment of Craniocerebral Injury Concurrent with Acute Kidney Injury

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• 作者：Yunxing Cao ; Jianwu Qiu ; Bing Wang ; Huanjiu Xi
• 关键词：Craniocerebral injury ; Acute kidney injury ; Cerebral tissue lesions ; Ambiguous ; Mortality ; Logistic regression analysis
• 刊名：Cell Biochemistry and Biophysics
• 出版年：2015
• 出版时间：January 2015
• 年：2015
• 卷：71
• 期：1
• 页码：199-204
• 全文大小：418 KB
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• 刊物主题：Biochemistry, general; Pharmacology/Toxicology; Biotechnology; Cell Biology; Biophysics and Biological Physics;
• 出版者：Springer US
• ISSN：1559-0283

文摘

The main objective of this study was to investigate the risk factors and clinical treatment of craniocerebral injury concurrent with acute kidney injury. A total of 220 patients who suffered from craniocerebral injury from March 2010 to March 2012 in our Hospital were prospectively analyzed. Craniocerebral injury was defined according to the medical history, the verification of CT, and some investigated scores. The acute kidney injury was defined as a relative 47?% increase?of?serum creatinine. The method of multivariate logistic regression analysis was used to evaluate the possible risk factors associated with post-craniocerebral injury concurrent with acute kidney injury. The clinical treatments of craniocerebral injury concurrent with acute kidney injury were also identified via experimental results, and the pathological mechanism of craniocerebral injury concurrent with acute kidney injury was found to be related to cerebral tissue lesions, but some potential factors were ambiguous. The incidence of acute kidney injury was 70.2?% with craniocerebral injury. In hospital, mortality of acute kidney injury patients was 31.2?%, which was 6.019 times of non-acute kidney injury patients (p?p?