Albumin administration in the acutely ill: what is new and where next?
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  • 作者:Jean-Louis Vincent (21)
    James A Russell (22)
    Matthias Jacob (23)
    Greg Martin (24)
    Bertrand Guidet (25) (26)
    Jan Wernerman (27)
    Ricard Ferrer Roca (28)
    Stuart A McCluskey (29)
    Luciano Gattinoni (30)

    21. Department of Intensive Care
    ; Erasme Hospital ; Universit茅 libre de Bruxelles ; route de Lennik 808 ; 1070 ; Brussels ; Belgium
    22. Center for Heart Lung Innovation and Critical Care Medicine
    ; University of British Columbia and St. Paul鈥檚 Hospital ; Vancouver ; Canada ; V6Z BC
    23. Department of Anaesthesiology
    ; University Hospital Munich ; Nussbaumstra脽e 20 ; 80336 ; Munich ; Germany
    24. Department of Medicine
    ; Division of Pulmonary ; Allergy and Critical Care ; Emory University School of Medicine ; Atlanta ; GA ; 30303 ; USA
    25. Service R茅animation M茅dicale
    ; H么pital Saint Antoine ; Universitaires Est Parisien ; Paris ; France
    26. Sorbonne Universit茅s
    ; UPMC Universit茅 Paris 06 ; UMR-S 1136 ; Institut Pierre Louis d鈥橢pid茅miologie et de Sant茅 Publique ; F-75013 ; Paris ; France
    27. Department of Anesthesiology & Intensive Care Medicine
    ; Karolinska University Hospital ; Huddinge ; 14186 ; Stockholm ; Sweden
    28. Servei de Medicina Intensiva
    ; Hospital Universitari M煤tua Terrassa ; Universitat de Barcelona ; CIBER Enfermedades Respiratorias ; 08221 ; Terrassa ; Barcelona ; Spain
    29. Department of Anesthesia and Pain Management
    ; Toronto General Hospital ; University of Toronto ; Toronto ; Ontario ; Canada ; M5G 2C4
    30. Dipartimento di Anestesia
    ; Rianimazione (Intensiva e Subintensiva) e Terapia del Dolore ; Fondazione IRCCS Ca鈥?Granda 鈥?Ospedale Maggiore Policlinico ; 20122 ; Milan ; Italy
  • 刊名:Critical Care
  • 出版年:2014
  • 出版时间:August 2014
  • 年:2014
  • 卷:18
  • 期:4
  • 全文大小:595 KB
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  • 刊物主题:Intensive / Critical Care Medicine; Emergency Medicine;
  • 出版者:BioMed Central
  • ISSN:1364-8535
文摘
Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate in more recent years. Importantly, all fluid solutions have potential benefits and drawbacks. Large multicenter randomized studies have provided valuable data regarding the safety of albumin solutions, and have begun to clarify which groups of patients are most likely to benefit from their use. However, many questions remain related to where exactly albumin fits within our fluid choices. Here, we briefly summarize some of the physiology and history of albumin use in intensive care before offering some evidence-based guidance for albumin use in critically ill patients.

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