Synthesis of Biodegradable Pyrazole, Pyran, Pyrrole, Pyrimidine and Chromene Derivatives having Medical and Surface Activities

详细信息    查看全文

• 作者：Refat El-Sayed
• 关键词：Synthesis ; Heterocyclic derivatives ; Surface activities
• 刊名：Journal of Surfactants and Detergents
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：19
• 期：6
• 页码：1153-1167
• 全文大小：768 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Industrial Chemistry and Chemical Engineering
  Surfaces and Interfaces and Thin Films
  Polymer Sciences
  Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
  Analytical Chemistry
  Physical Chemistry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1558-9293
• 卷排序：19

文摘

In this research, stearic acid and propylene oxide are used to synthesize biodegradable heterocyles (pyrazole, pyran, chromene, and pyrimidine) to improve their solubility and lower their toxicity. The chemical structure of these surfactants was confirmed using IR, 1H, and 13C NMR spectra. Some of these compounds have higher activity than commercial antibiotics and may be useful in the pharmaceutical industry.