Dendritic Core-Multishell Nanocarriers in Murine Models of Healthy and Atopic Skin
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- 作者：Moritz Radbruch ; Hannah Pischon ; Anja Ostrowski ; Pierre Volz…
- 关键词：CMS ; Skin ; Topical treatment ; Dermal delivery ; Atopic dermatitis ; Oxazolone ; Fluorescence lifetime imaging microscopy ; Nanomaterials ; Multi ; domain nanoparticles ; Penetration enhancement
- 刊名：Nanoscale Research Letters
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：12
- 期：1
- 全文大小：9584KB
- 刊物主题：Nanotechnology; Nanotechnology and Microengineering; Nanoscale Science and Technology; Nanochemistry; Molecular Medicine;
- 出版者：Springer US
- ISSN：1556-276X
- 卷排序：12
文摘
Dendritic hPG-amid-C18-mPEG core-multishell nanocarriers (CMS) represent a novel class of unimolecular micelles that hold great potential as drug transporters, e.g., to facilitate topical therapy in skin diseases. Atopic dermatitis is among the most common inflammatory skin disorders with complex barrier alterations which may affect the efficacy of topical treatment.