Successful control of juvenile dermatomyositis-associated macrophage activation syndrome and interstitial pneumonia: distinct kinetics of interleukin-6 and -18 levels
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- 作者：Hiroyuki Wakiguchi ; Shunji Hasegawa ; Reiji Hirano…
- 关键词：Cytokine ; Juvenile dermatomyositis ; Macrophage activation syndrome ; Autoimmune ; associated hemophagocytic lymphohistiocytosis ; Interstitial pneumonia ; IL ; 18 ; IL ; 6 ; KL ; 6
- 刊名：Pediatric Rheumatology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：13
- 期：1
- 全文大小：859 KB
- 刊物主题：Pediatrics; Rheumatology;
- 出版者：BioMed Central
- ISSN：1546-0096
文摘
Background Macrophage activation syndrome (MAS) is the secondary hemophagocytic lymphohistiocytosis associated with rheumatic diseases. Recently, the different cytokine profiles between systemic juvenile idiopathic arthritis (sJIA)-associated MAS (sJIA-MAS) and juvenile systemic lupus erythematosus (JSLE)-associated MAS (JSLE-MAS) were reported. However, there is little information about juvenile dermatomyositis (JDM)-associated MAS (JDM-MAS).