Comparative speed of kill of sarolaner (Simparica₿ and afoxolaner (NexGard®) against induced infestations of Rhipicephalus sanguineus s.l. on dogs
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- 作者：Robert H. Six ; David R. Young ; Susan J. Holzmer ; Sean P. Mahabir
- 关键词：Rhipicephalus sanguineus sensu lato ; Brown dog tick ; Sarolaner ; Simparica™ Afoxolaner ; Oral ; Speed of kill ; Isoxazoline
- 刊名：Parasites & Vectors
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：9
- 期：1
- 全文大小：926 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine; Entomology;
- 出版者：BioMed Central
- ISSN：1756-3305
文摘
Background The brown dog tick, Rhipicephalus sanguineus sensu lato, commonly infests dogs globally, is the major vector of the pathogen that causes canine monocytic ehrlichiosis and also transmits Babesia vogeli. A rapid speed of kill of a parasiticide is essential to reduce the direct deleterious effects of tick infestation and the risk of tick-borne pathogen transmission. The speed of kill of a novel orally administered isoxazoline parasiticide, sarolaner (Simparica™), against R. sanguineus sensu lato on dogs was evaluated and compared with afoxolaner (NexGard®) for 5 weeks after a single oral dose.