Influence of sympathectomy on human peripheral nerve regeneration after autoneuroplasty

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• 作者：M. V. Merculov ; I. O. Golubev ; A. I. Krupatkin
• 关键词：sympathectomy ; nerve trophism ; microcirculation ; nerve regeneration
• 刊名：Human Physiology
• 出版年：2015
• 出版时间：March 2015
• 年：2015
• 卷：41
• 期：2
• 页码：190-195
• 全文大小：167 KB
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• 作者单位：M. V. Merculov (1)
  I. O. Golubev (1)
  A. I. Krupatkin (1)
  
  1. Priorov Central Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Moscow, Russia
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Life Sciences
  Human Physiology
  Biomedicine
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3164

文摘

86 patients with posttraumatic defects of the median and ulnar nerves were examined. Autoneuroplasty was performed in all patients: in 42 patients, in combination with sympathectomy (thoracoscopic clipping of the Th3-em class="EmphasisTypeItalic">Th4 sympathetic trunk ganglia); in 44 patients, without sympathectomy. Ultrasonography of nerve trunks, stimulation electroneuromyography, computer thermography, and laser Doppler flowmetry with a spectral wavelet analysis of blood flow oscillations were used in the examination. It was demonstrated that sympathectomy has a positive activating effect on the recovery of innervation and tissue trophism in the process of posttraumatic regeneration of peripheral nerves. A combination of autoneuroplasty with sympathectomy promotes a more complete recovery of motor and sensory nerve fibers, normalization of blood flow in the microvascular bed, and thermal topography of the damaged limb segment, including those in the area of previously denervated tissues.