Green synthesis of starch-mediated CuO nanoparticles: preparation, characterization, antimicrobial activities and in vitro MTT assay against MCF-7 cell line

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• 作者：Hossein Alishah ; Shahram Pourseyedi ; S. Yousef Ebrahimipour…
• 关键词：Nanostructures ; X ; ray diffraction transmission electron microscopy (TEM) ; Sol–gel chemistry
• 刊名：Rendiconti Lincei
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：28
• 期：1
• 页码：65-71
• 全文大小：
• 刊物类别：Earth and Environmental Science
• 刊物主题：Environment, general; Earth Sciences, general; Life Sciences, general; Biomedicine, general; History of Science;
• 出版者：Springer International Publishing
• ISSN：1720-0776
• 卷排序：28

文摘

The main goal of this study was the synthesis of copper oxide nanoparticles with a green method using Starch extracted from Solanum tuberosum. The synthesized copper oxide nanoparticles were characterized by different techniques, including X-ray diffraction (XRD), UV–Vis spectrophotometry, and scanning electron microscopy (SEM). All the analyses exposed that the nanoparticles were highly stable and spherical with mean size about 54 nm. The potential antibacterial activity of the copper oxide nanoparticles synthesized in the eco-friendly approach was tested against some standard strains of human pathogens (Gram-positive and -negative bacteria). Efficient antibacterial activities against Bacillus cereus 9634, Shigella sonnei, Staphylococcus epidermidis 1435, Enterococcus 1237, Pseudomonas aeruginosa PAO1 27853 and Escherichia coli 25922 and no significant antibacterial activity against Staphylococcus aureus 2592 were observed. Moreover, MTT assay demonstrated the anticancer activity ofthat the synthesized CuO nanoparticles against MCF-7 cell line.