Diffuse alveolar hemorrhage after use of a fluoropolymer-based waterproofing spray

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• 作者：Ryota Kikuchi ; Masayuki Itoh ; Tomonori Uruma ; Takao Tsuji…
• 关键词：Alveolar hemorrhage ; Waterproofing spray ; Fluoropolymer ; Respiratory insufficiency ; Dyspnea
• 刊名：SpringerPlus
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：4
• 期：1
• 全文大小：1018KB
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• 作者单位：Ryota Kikuchi (1)
  Masayuki Itoh (1)
  Tomonori Uruma (1)
  Takao Tsuji (1)
  Hidehiro Watanabe (1)
  Hiroyuki Nakamura (1)
  Kazutetsu Aoshiba (1)
  
  1. Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuou, Ami, Inashiki, Ibaraki, 300-0395, Japan
  
• 刊物类别：Science, general;
• 刊物主题：Science, general;
• 出版者：Springer International Publishing
• ISSN：2193-1801

文摘

A 30-year-old man developed chills, cough and dyspnea a few minutes after using a fluoropolymer-based waterproofing spray in a small closed room. He visited our hospital 1 h later. Examination revealed that the patient had incessant cough, tachypnea, fever and decreased peripheral arterial oxygen saturation. Blood tests revealed leukocytosis with elevated serum C-reactive protein levels. Chest radiographs and computed tomography (CT) scan showed bilateral ground glass opacities, mainly in the upper lobes. Bronchoalveolar lavage (BAL) fluid obtained from the right middle lobe showed a bloody appearance. Microscopic examination of a BAL cytospin specimen revealed the presence of numerous red blood cells associated with extreme neutrophilia. Microbiological studies of the BAL fluid were negative. The patient was observed without corticosteroid therapy, and his symptoms and abnormal shadows on the chest radiographs and CT improved. On day 7 after admission, the patient was discharged from the hospital. Accidental inhalation of waterproofing spray may cause diffuse alveolar hemorrhage, a rare manifestation of acute lung injury. Supportive treatment may be effective and sufficient. Keywords Alveolar hemorrhage Waterproofing spray Fluoropolymer Respiratory insufficiency Dyspnea