Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the Generation R Study
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- 作者：Jolien Steenweg-de Graaff ; Sabine J. Roza…
- 关键词：Folate ; Folic acid supplementation ; Pregnancy ; Foetal neurodevelopment ; Head growth ; Head size
- 刊名：European Journal of Nutrition
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：56
- 期：1
- 页码：65-75
- 全文大小：412KB
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Nutrition;
- 出版者：Springer Berlin Heidelberg
- ISSN：1435-1293
- 卷排序：56
文摘
PurposeFolic acid supplementation during pregnancy has been associated with a reduced risk of common neurodevelopmental delays in the offspring. However, it is unclear whether low folate status has effects on the developing brain. We evaluated the associations of maternal folic acid supplementation and folate concentrations during pregnancy with repeatedly measured prenatal and postnatal head circumference in the offspring.