Biodegradable stereocomplex polylactide having flexible ?-caprolactone unit

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• 作者：Min Kyu Kang (1) (2)
  Youngmee Jung (1)
  Soo Hyun Kim (1) (2) (3)
  
• 关键词：stereocomplex formation ; copolymerization ; supercritical fluid
• 刊名：Macromolecular Research
• 出版年：2013
• 出版时间：September 2013
• 年：2013
• 卷：21
• 期：9
• 页码：1036-1041
• 全文大小：571KB
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• 作者单位：Min Kyu Kang (1) (2)
  Youngmee Jung (1)
  Soo Hyun Kim (1) (2) (3)
  
  1. Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, 136-791, Korea
  2. University of Science and Technology, Daejeon, 305-333, Korea
  3. Graduate School, Korea University, Seoul, 136-701, Korea
  
• ISSN：2092-7673

文摘

Stereocomplex formation between poly(L-lactide-co-?-caprolactone) (PLLCL) and poly(D-lactide-co-?-caprolactone) (PDLCL) is known to be disturbed when their molecular weights increase to >105 g/mol. Here, Strong and biodegradable stereocomplexes of copolymers (S-PLCL) were studied using a supercritical fluid and co-solvent system. Mechanical properties such as tensile strength were ?.5 times increased due to high degree of stereocomplex than those of PLGA20. The addition of the flexible ?-caprolactone units to the polylactide increased its thermal stability which significantly enhanced 100% degree of stereocomplex after 2nd melt processing through DSC due to the increased mobillity of the polylactide’s chains. The degradation behavior of resulting biodegradable S-PLCL showed slow degradation with increasing CL content in 0.13 M, pH 4.3 phosphate buffers.