Fructose-enriched diet induces inflammation and reduces antioxidative defense in visceral adipose tissue of young female rats
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- 作者：Sanja Kovačević ; Jelena Nestorov ; Gordana Matić…
- 关键词：Fructose diet ; Inflammation ; NF ; κB ; Visceral adipose tissue ; Oxidative stress ; Female rats
- 刊名：European Journal of Nutrition
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：56
- 期：1
- 页码：151-160
- 全文大小：
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Nutrition;
- 出版者：Springer Berlin Heidelberg
- ISSN：1435-1293
- 卷排序：56
文摘
PurposeThe consumption of refined, fructose-enriched food continuously increases and has been linked to development of obesity, especially in young population. Low-grade inflammation and increased oxidative stress have been implicated in the pathogenesis of obesity-related disorders including type 2 diabetes. In this study, we examined alterations in inflammation and antioxidative defense system in the visceral adipose tissue (VAT) of fructose-fed young female rats, and related them to changes in adiposity and insulin sensitivity.