Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids
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- 作者：Junjie Yang ; Sheng Yang
- 关键词：Corynebacterium glutamicum ; Pan ; genome ; Comparative genomics ; Production of amino acids
- 刊名：BMC Genomics
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：18
- 期：1-supp
- 全文大小：567KB
- 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
- 出版者：BioMed Central
- ISSN：1471-2164
- 卷排序：18
文摘
BackgroundCorynebacterium glutamicum is a non-pathogenic bacterium widely used in industrial amino acid production and metabolic engineering research. Although the genome sequences of some C. glutamicum strains are available, comprehensive comparative genome analyses of these species have not been done. Six wild type C. glutamicum strains were sequenced using next-generation sequencing technology in our study. Together with 20 previously reported strains, we present a comprehensive comparative analysis of C. glutamicum genomes.