Safety of etanercept therapy in rheumatoid patients undergoing surgery: preliminary report

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• 作者：Salvatore Corrao ; Giovanni Pistone ; Sabrina Arnone ; Luigi Calvo ; Rosario Scaglione and Giuseppe Licata
• 关键词：Anti ; rheumatic agents ; Etanercept ; Patient satisfaction ; Rheumatoid arthritis ; Surgery
• 刊名：Clinical Rheumatology
• 出版年：2007
• 出版时间：September, 2007
• 年：2007
• 卷：26
• 期：9
• 页码：1513-1515
• 全文大小：66 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Rheumatology
  
• 出版者：Springer London
• ISSN：1434-9949

文摘

This is a preliminary report on a case-series of rheumatoid patients that underwent various kinds of elective surgery but did not withdraw etanercept therapy in spite of physician advise. Elective surgery consisted of right knee surgical prosthesis, bilateral cataract, bilateral hallux valgus, right hip prosthesis, bladder stone by cystoscopy and left inguinal hernia. All the patients had a regular healing rate. During follow-up (6–12 months) no one of these patients were suffering from infective complications after surgery. According to same recent literature results, our data suggest that it is the time to value rheumatoid patient preferences through a correct information about cost-benefit of this treatment to establish together with patients if etanercept therapy has to be discontinued before and after elective surgery. Finally, we think that adverse drug reaction surveillance has to be boosted, and editors of leading scientific journal should publish more papers on case-series about drug safety and tolerability in particular conditions.