Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase
详细信息    查看全文
  • 作者:Christian Weyler ; Matthias Bureik ; Elmar Heinzle
  • 关键词:Biocatalysis ; Permeabilized cells ; Schizosaccharomyces pombe ; Selective oxidation ; UDP ; glucose ; 6 ; dehydrogenase ; UDP ; glucuronate
  • 刊名:Biotechnology Letters
  • 出版年:2016
  • 出版时间:March 2016
  • 年:2016
  • 卷:38
  • 期:3
  • 页码:477-481
  • 全文大小:812 KB
  • 参考文献:Banerjee N, Bhattacharyya D (2011) UDP-glucose dehydrogenase from Capra hircus liver: purification, partial characterization and evaluation as a coupling enzyme in UDP-galactose 4-epimerase assay. J Mol Catal B 68:37–43CrossRef
    Buchheit D, Dragan CA, Schmitt EI, Bureik M (2011a) Production of ibuprofen acyl glucosides by human UGT2B7. Drug Metab Dispos 39:2174–2181CrossRef PubMed
    Buchheit D, Schmitt EI, Bischoff D, Ebner T, Bureik M (2011b) S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in genetically engineered fission yeast cells. Biol Chem 392:1089–1095CrossRef PubMed
    Dragan C-A, Zearo S, Hannemann F, Bernhardt R, Bureik M (2005) Efficient conversion of 11-deoxycortisol to cortisol (hydrocortisone) by recombinant fission yeast Schizosaccharomyces pombe. FEMS Yeast Res 5:621–625CrossRef PubMed
    Dragan CA, Buchheit D, Bischoff D, Ebner T, Bureik M (2010) Glucuronide production by whole-cell biotransformation using genetically engineered fission yeast Schizosaccharomyces pombe. Drug Metab Dispos 38(3):509–515CrossRef PubMed
    Egger S, Chaikuad A, Kavanagh KL, Oppermann U, Nidetzky B (2010) UDP-glucose dehydrogenase: structure and function of a potential drug target. Biochem Soc Trans 38:1378–1385CrossRef PubMed
    Engels L, Henze M, Hummel W, Elling L (2015) Enzyme module systems for the synthesis of uridine 5′-diphospho-α-d-glucuronic Acid and non-sulfated human natural killer cell-1 (HNK-1) epitope. Adv Synth Catal 357(8):1751–1762CrossRef
    Glaser L, Melo A, Paul R (1967) Uridine diphosphate sugar hydrolase. Purification of enzyme and protein inhibitor. J Biol Chem 242(8):1944–1954PubMed
    Guo YX, Fang JQ, Li TH, Li X, Ma C, Wang X, Wang PG, Li L (2015) Comparing substrate specificity of two UDP-sugar pyrophosphorylases and efficient one-pot enzymatic synthesis of UDP-GlcA and UDP-GalA. Carbohydr Res 411:1–5CrossRef PubMed
    Heinzle E, Weyler C, Krauser S, Blaß LK (2013) Directed multistep biocatalysis using tailored permeabilized cells. In: Zeng A-P (ed) Fundamentals and application of new bioproduction systems. Springer, Berlin, pp 185–234
    Hempel J (1994) Uridine diphosphoglucose dehydrogenase from rat liver: purification and effect of pH on regulatory properties. Protein Sci 3:1074–1080PubMedCentral CrossRef PubMed
    Hummel W, Riebel B (2003) Isolation and biochemical characterization of a new NADH oxidase from Lactobacillus brevis. Biotechnol Lett 25:51–54CrossRef PubMed
    Hung RJ, Chien HS, Lin RZ, Lin CT, Vatsyayan J, Peng HL, Chang HY (2007) Comparative analysis of two UDP-glucose dehydrogenases in Pseudomonas aeruginosa PAO1. J Biol Chem 282:17738–17748CrossRef PubMed
    Krauser S, Kiefer P, Heinzle E (2012) Multienzyme whole-cell in situ biocatalysis for the production of flaviolin in permeabilized cells of Escherichia coli. Chemcatchem 4(6):786–788CrossRef
    Losson R, Lacroute F (1983) Plasmids carrying the yeast OMP decarboxylase structural and regulatory genes: transcription regulation in a foreign environment. Cell 32:371–377CrossRef PubMed
    Proudfoot M, Kuznetsova E, Brown G, Rao NN, Kitagawa M, Mori H, Savchenko A, Yakunin AF (2004) General enzymatic screens identify three new nucleotidases in Escherichia coli. J Biol Chem 279:54687–54694CrossRef PubMed
    Tanaka H, Yoshimura Y, Jorgensen MR, Cuesta-Seijo JA, Hindsgaul O (2012) A simple synthesis of sugar nucleoside diphosphates by chemical coupling in water. Angew Chem Int Ed Engl 51(46):11531–11534CrossRef PubMed
    Weyler C, Heinzle E (2015) Multistep synthesis of UDP-glucose using tailored, permeabilized cells of E. coli. Appl Biochem Biotechnol 175:3729–3736CrossRef PubMed
    Yuan Y, Heinzle E (2009) Permeabilization of Corynebacterium glutamicum for NAD(P)H-dependent intracellular enzyme activity measurement. Comptes Rend Chim 12:1154–1162CrossRef
  • 作者单位:Christian Weyler (1)
    Matthias Bureik (2)
    Elmar Heinzle (1)

    1. Biochemical Engineering Institute, Saarland University, Campus A1.5, 66123, Saarbrücken, Germany
    2. School of Pharmaceutical Science and Technology (SPST), Tianjin University, Building 24, 92 Weijin Road, Nankai District, Tianjin, 300072, People’s Republic of China
  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Life Sciences
    Microbiology
    Biotechnology
    Applied Microbiology
    Biochemistry
  • 出版者:Springer Netherlands
  • ISSN:1573-6776
文摘
Objectives To use permeabilized cells of the fission yeast, Schizosaccharomyces pombe, that expresses human UDP-glucose 6-dehydrogenase (UGDH, EC 1.1.1.22), for the production of UDP-glucuronic acid from UDP-glucose.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700