Circulating angiopoietin-like protein 8 (ANGPTL8) and ANGPTL3 concentrations in relation to anthropometric and metabolic profiles in Korean children: a prospective cohort study

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• 作者：Hye Soo Chung ; Min Jung Lee ; Soon Young Hwang ; Hyun Jung Lee…
• 关键词：ANGPTL3 ; ANGPTL8 ; Cholesterol ; Dyslipidemias ; HDL ; LDL ; Triglycerides
• 刊名：Cardiovascular Diabetology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：15
• 期：1
• 全文大小：858 KB
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• 作者单位：Hye Soo Chung (1)
  Min Jung Lee (1)
  Soon Young Hwang (2)
  Hyun Jung Lee (1)
  Hye Jin Yoo (1)
  Ji-A Seo (1)
  Sin Gon Kim (1)
  Nan Hee Kim (1)
  Sei Hyun Baik (1)
  Dong Seop Choi (1)
  Seon Mi Kim (3)
  Kyung Mook Choi (1)
  
  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea
  2. Department of Biostatistics, College of Medicine, Korea University, Seoul, Korea
  3. Department of Family Medicine, College of Medicine, Korea University, Seoul, Korea
  
• 刊物主题：Diabetes; Angiology; Cardiology;
• 出版者：BioMed Central
• ISSN：1475-2840

文摘

Background Previous studies have shown that angiopoietin-like protein 8 (ANGPTL8), also called as betatrophin, acts together with ANGPTL3 to regulate lipid metabolism, glucose metabolism, and energy homeostasis. Moreover, ANGPTL8 promotes proliferation of pancreatic β-cells and induces insulin secretion. However, there are no previous longitudinal studies in humans.