Effect of aripiprazole, risperidone, and olanzapine on the acoustic startle response in Japanese chronic schizophrenia
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- 作者：Taro Kishi ; Masatsugu Moriwaki ; Tsuyoshi Kitajima ; Kunihiro Kawashima ; Tomo Okochi ; Yasuhisa Fukuo ; Osamu Furukawa ; Hiroshi Naitoh ; Kiyoshi Fujita and Nakao Iwata
- 关键词：Acoustic startle response ; Risperidone ; Aripiprazole ; Olanzapine ; Schizophrenia ; Prepulse inhibition ; Antipsychotic
- 刊名：Psychopharmacology
- 出版年：2010
- 出版时间：April, 2010
- 年：2010
- 卷：209
- 期：2
- 页码：185-190
- 全文大小：138.6 KB
文摘
Background Studies have also shown that differences in the kind of the antipsychotics influenced disruption of the sensorimotor gating system, including prepulse inhibition (PPI), acoustic startle reflex (ASR), and habituation (HAB). We investigated the influence on startle response in chronic schizophrenia in 20 patients with schizophrenia taking risperidone, 21 patients with schizophrenia taking olanzapine, and 20 patients with schizophrenia taking aripiprazole.