RNAe in a transgenic growth hormone mouse model shows potential for use in gene therapy

详细信息    查看全文

• 作者：Haizhou Long ; Yi Yao ; Shouhong Jin ; Yingting Yu ; Xiongbing Hu…
• 关键词：Growth hormone ; Pharmaceutical application ; Protein production ; RNAe ; Transgenic mice
• 刊名：Biotechnology Letters
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：39
• 期：2
• 页码：179-188
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
• 出版者：Springer Netherlands
• ISSN：1573-6776
• 卷排序：39

文摘

ObjectiveRNAe is a new method that enhances protein expression at the post-transcriptional level. RNAe utility was further explored to improve endogenous protein expression.