Comparison of Hypoglycemic Activity of Fermented Mushroom of Inonotus obliquus Rich in Vanadium and Wild-Growing I. obliquus

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• 作者：Yibing Zhang (1)
  Yong Zhao (2)
  Haifeng Cui (2)
  Chunyu Cao (2)
  Jianyou Guo (3)
  Sha Liu (1)
  
• 关键词：Vanadium ; Inonotus obliquus ; AAS ; Blood glucose
• 刊名：Biological Trace Element Research
• 出版年：2011
• 出版时间：December 2011
• 年：2011
• 卷：144
• 期：1-3
• 页码：1351-1357
• 全文大小：152KB
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• 作者单位：Yibing Zhang (1)
  Yong Zhao (2)
  Haifeng Cui (2)
  Chunyu Cao (2)
  Jianyou Guo (3)
  Sha Liu (1)
  
  1. School of Traditional Chinese Medicine, Chongqing Medical University, Jieqing Road, Huxi University City, Chongqing, 401331, People’s Republic of China
  2. Institute of Chinese Materia Medica, China Academy of TCM, Beijing, 100700, People’s Republic of China
  3. Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China
  

文摘

The effects of vanadium-enriched and wild Inonotus obliquus were tested on hyperglycemic mice. The vanadium content of the culture medium was 0.6%, reaching a concentration of 3.0?mg/g in the cultured mushroom while in the wild variety is 1/100 of that amount. The toxicity of vanadium at the 3.0?mg/g level is negligible, but its anti-diabetic effects are significantly different to those of the wild variety (p-lt;-.05). Due to its high bioavailability and low toxicity, vanadium-enriched I. obliquus could be used as a means of vanadium supplementation, with expectation of obtaining higher bioavailability and lower toxicity in animals.