Treatment of Hepatic Adenomatosis

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• 作者：Claire Meyer ; Mauricio Lisker-Melman
• 关键词：Hepatic adenomatosis ; Liver adenomatosis ; Treatment of hepatic adenomatosis ; Management of liver adenomatosis
• 刊名：Current Hepatitis Reports
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：14
• 期：2
• 页码：139-143
• 全文大小：143 KB
• 参考文献：Papers of particular interest, published recently, have been highlighted as: -Of importance1.Flejou JF, Barge J, Menu Y, Degott C, Bismuth H, Potet F, et al. Liver adenomatosis. An entity distinct from liver adenoma? Gastroenterology. 1985;89(5):1132-.PubMed
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  22.Battula N, Tsapralis D, Takhar A, Coldham C, Mayer D, Isaac J, et al. Aetio-pathogenesis and the management of spontaneous liver bleeding in the West: a 16-year single-centre experience. HPB (Oxford). 2012;14(6):382-.View Article
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• 作者单位：Claire Meyer (1)
  Mauricio Lisker-Melman (1)
  
  1. Division of Gastroenterology, Washington University School of Medicine, 660 South Euclid Ave, Box 8124, St. Louis, MO, 63110, USA
  
• 刊物主题：Hepatology;
• 出版者：Springer US
• ISSN：1541-0706

文摘

Hepatic adenomatosis and hepatocellular adenomas share risk factors and the same pathophysiologic spectrum. The presence in the liver of 10 hepatocellular adenomas defines hepatic adenomatosis. The diagnosis may be established incidentally during a liver radiologic examination in the asymptomatic patient, or after associated right upper quadrant pain, hepatomegaly or liver test abnormalities. Upon the diagnosis of hepatic adenomatosis or either of its life-threatening complications—hemorrhage and progression to hepatocellular carcinoma—consideration should be given to potential medical, radiologic, and surgical interventions including observation (estrogen and androgen withdrawal), resection, transarterial embolization, radiofrequency ablation, and liver transplantation. The management of patients with hepatic adenomatosis can be challenging. These patients should be ideally referred to centers with expertise in the management of liver diseases.