3D black blood VISTA vessel wall cardiovascular magnetic resonance of the thoracic aorta wall in young, healthy adults: reproducibility and implications for efficacy trial sample sizes: a cross-sectional study
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- 作者：Anouk L. M. Eikendal ; Björn A. Blomberg…
- 关键词：3D ; Black ; blood ; CMR ; Reproducibility ; Young ; Healthy ; Atherosclerosis ; Aorta ; Characteristics
- 刊名：Journal of Cardiovascular Magnetic Resonance
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：2,784 KB
- 刊物主题：Imaging / Radiology; Angiology; Cardiology;
- 出版者：BioMed Central
- ISSN：1532-429X
- 卷排序：18
文摘
BackgroundPre-clinical detection of atherosclerosis enables personalized preventive strategies in asymptomatic individuals. Cardiovascular magnetic resonance (CMR) has evolved as an attractive imaging modality for studying atherosclerosis in vivo. Yet, the majority of aortic CMR studies and proposed sequences to date have been performed at 1.5 tesla using 2D BB techniques and a slice thickness of 4–5 mm. Here, we evaluate for the first time the reproducibility of an isotropic, T1-weighted, three-dimensional, black-blood, CMR VISTA sequence (3D-T1-BB-VISTA) for quantification of aortic wall characteristics in healthy, young adults.