DNA-binding and photocleavage studies of metallofluorescein–porphyrin complexes of zinc(II) and copper(II)

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• 作者：Jiazheng Lu (1) lujia6812@163.com
  Weijian Pan (1)
  Rongwei He (1)
  Shuqiang Jin (1)
  Xiangwen Liao (1)
  Bin Wu (2)
  Ping Zhao (3) zhaoping666@163.com
  Haiwei Guo (1)
• 刊名：Transition Metal Chemistry
• 出版年：2012
• 出版时间：August 2012
• 年：2012
• 卷：37
• 期：5
• 页码：497-503
• 全文大小：418.9 KB
• 参考文献：1. Waskitoaji W, Hyakutake T, Kato J, Watanabe M, Nishide H (2009) Chem Lett 38:1164–1165
  2. Shieh MJ, Peng CL, Lou PJ, Chiu CH, Tsai TY, Hsu CY, Yeh CY, Lai PS (2008) J Control Release 7:200–206
  3. Poon CT, Zhao S, Wong WK, Kwong DWJ (2010) Tetrahedron Lett 51:664–668
  4. Yedukondalu M, Ravikanth M (2011) Coord Chem Rev 255:547–573
  5. Fiel RJ (1989) Porphyrin–nucleic acid interactions: a review. J Biomol Struct Dyn 6:1259–1273
  6. Ishikawa Y, Yamakawa N, Uno T (2002) Bioorg Med Chem 10:1953–1960
  7. D’Urso A, Mammana A, Balaz M, Holmes AE, Berova N, Lauceri R, Purrello R (2009) J Am Chem Soc 131:2046–2047
  8. Li ZP, Xing YH, Zhang YH, Zhou GH et al (2009) J Coord Chem 62(4):564–576
  9. Efthimiadou EK, Katsaros N, Karaliota A, Psomas G (2007) Bioorg Med Chem Lett 17:1238–1243
  10. Benítez J, Guggeri L, Tomaz I, Pessoa JC, Moreno V, Lorenzo J (2009) J Inorg Biochem 103:1386–1390
  11. Nejo AA, Kolawole GA, Opoku AR, Wolowska J, O’Brien P (2009) Inorg Chem Acta 362:3993–3998
  12. McCrate A, Carlone M, Nielsen M, Swavey S (2010) Inorg Chem Commun 13:537–539
  13. Vaz Serra V, Zamarrón A, Faustino MAF, Iglesias-de la Cruz MC, Blázquez A, Rodrigues JMM (2010) Bioorg Med Chem 18:6170–6178
  14. Kelly TM, Tossi AB, McConnell DJ, Strekas TC (1985) Nucleic Acids Res 13:6017
  15. Sternberg ED, Dolphin D, Bruckner C (1998) Tetrahedron 54:4151–4202
  16. Oda K, Ogura S, Okura I (2000) J Photochem Photobiol B 59:20–25
  17. Mez? G, Herényi L, Habdas J, Majer Z, Kurdziel BM, Tóthf K, Csík G (2011) Biophys Chem 155:36–44
  18. Mettath S, Munson BR, Pandey RK (1999) Bioconjug Chem 10:94–102
  19. Yan XB, Weng M, Zhang MH, Shen T (1998) Dyes Pigm 36(3):259–272
  20. Lu JZ, Tan XC, Huang JW, Dong CH (2005) Trans Met Chem 30:643–649
  21. Lu JZ, Du YF, Wu B, Huang JW, Jiang J (2010) Trans Met Chem 35:451–456
  22. Lu JZ, Huang JW, Fan LF, Liu J, Chen XL, Ji LN (2004) Inorg Chem Commun 7(9):1030–1033
  23. Zhao P, Xu LC, Huang JW, Fu B, Yu HC, Ji LN (2008) Bioorg Chem 36:278–287
  24. Lu JZ, Du YF, Guo HW (2011) J Coord Chem 64(7):1229–1239
  25. Du YF, Lu JZ, Guo HW, Jiang J (2010) Trans Met Chem 35:859–864
  26. Daryono HT, Shunsuke M, Takehiro A, Naoki Y, Hidenari I (2001) J Inorg Biochem 85:219–228
  27. Pasternack RF, Gibbs EJ, Villafrancas JJ (1983) Biochemistry 22:2406–2414
  28. ?eha D, Kabelá?ek M, Ryjá?ek F, ?poner J, ?poner JE, Elstner M, Suhai S, Hobza P (2002) J Am Chem Soc 124:3366–3376
  29. Feng R, Konishi YS (1993) J Am Soc Mass Spectrom 4:638–642
  30. Li T, Huang JW, Ma L, Ji LN (2003) Trans Met Chem 28:288–291
  31. Chen B, Qin W, Wang P, Tian T, Ma HJ, Cao XP, Wu XJ, Zhou X, Zhang XL, Liu F, Zheng F, Li X (2003) Bioorg Med Chem Lett 13:3731–3733
  32. Al-Azemi TF, Vinodh M (2011) Tetrahedron 67:2585–2590
  33. Mehta G, Muthusamy S, Maiya BG, Arounaguiri S (1997) Tetrahedron Lett 38:7125–7129
  34. Angelov D, Beylot B, Spassky A (2005) Biophys J 88:2766–2770
• 作者单位：1. School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006 People’s Republic of China2. The Peoples-Hospital of Shiling Huadu District, Guangzhou, 510850 Guangdong, People’s Republic of China3. School of Medicine Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Guangzhou, 510006 People’s Republic of China
• ISSN：1572-901X

文摘

The DNA-binding behaviors of the fluorescein–porphyrinatozinc(II) complex Zn(Fl-PPTPP) (Fl-PPTPP = 5-(4-fluoresceinpropyloxy)phenyl-10,15,20-triphenylporphyrin) and fluorescein–porphyrinatocopper(II) complex Cu(Fl-PPTPP) with calf thymus DNA (CT-DNA) were investigated by UV–Vis absorption titrations, fluorescence spectra, viscosity measurements, thermal denaturation and circular dichroism. The results suggest that both complexes interact with CT-DNA by intercalation. In addition, their photocleavage reactions with pBR322 supercoiled plasmid DNA were investigated. Both complexes exhibit significant DNA cleavage activity, and singlet oxygen may play an important role in these reactions.