Relationship of Blood Levels of Pb with Cu, Zn, Ca, Mg, Fe, and Hb in Children Aged 0??Years from Wuhan, China
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- 作者：Jingping Ye ; Chuang Du ; Lu Wang ; Zhen Li…
- 关键词：Blood ; Children ; Lead ; Essential element ; Hemoglobin
- 刊名：Biological Trace Element Research
- 出版年：2015
- 出版时间：March 2015
- 年：2015
- 卷：164
- 期：1
- 页码：18-24
- 全文大小：189 KB
- 参考文献：1. Cobanoglu, U, Demir, H, Sayir, F, Duran, M, Mergan, D (2010) Some mineral, trace element and heavy metal concentrations in lung cancer. Asian Pac J Cancer Prev 11: pp. 1383-1388
2. Renzi, M, Perra, G, Guerranti, C, Mariottini, M, Baroni, D, Volterrani, M, Graziosi, M, Specchiulli, A, Focardi, S (2009) Assessment of environmental pollutants in ten southern Italy harbor sediments. Toxicol Ind Health 25: pp. 351-363 CrossRef
3. Staessen, J, Yeoman, WB, Fletcher, AE, Markowe, HL, Marmot, MG, Rose, G, Semmence, A, Shipley, MJ, Bulpitt, CJ (1990) Blood lead concentration, renal function, and blood pressure in London civil servants. Br J Ind Med 47: pp. 442-447
4. Al-Neamy, FR, Almehdi, AM, Alwash, R, Pasha, MA, Ibrahim, A, Bener, A (2001) Occupational lead exposure and amino acid profiles and liver function tests in industrial workers. Int J Environ Health Res 11: pp. 181-188 CrossRef
5. Herman, DS, Geraldine, M, Venkatesh, T (2007) Evaluation, diagnosis, and treatment of lead poisoning in a patient with occupational lead exposure: a case presentation. J Occup Med Toxicol 2: pp. 7 CrossRef
6. Bonde, JP, Joffe, M, Apostoli, P, Dale, A, Kiss, P, Spano, M, Caruso, F, Giwercman, A, Bisanti, L, Porru, S, Vanhoorne, M, Comhaire, F, Zschiesche, W (2002) Sperm count and chromatin structure in men exposed to inorganic lead: lowest adverse effect levels. Occup Environ Med 59: pp. 234-242 CrossRef
7. Martin, D, Glass, TA, Bandeen-Roche, K, Todd, AC, Shi, W, Schwartz, BS (2006) Association of blood lead and tibia lead with blood pressure and hypertension in a community sample of older adults. Am J Epidemiol 163: pp. 467-478 CrossRef
8. Chiodo, LM, Jacobson, SW, Jacobson, JL (2004) Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol Teratol 26: pp. 359-371 CrossRef
9. Khan, DA, Qayyum, S, Saleem, S, Ansari, WM, Khan, FA (2010) Lead exposure and its adverse health effects among occupational worker’s children. Toxicol Ind Health 26: pp. 497-504 CrossRef
10. Rohlman, DS, Anger, WK, Tamulinas, A, Phillips, J, Bailey, SR, McCauley, L (2001) Development of a neurobehavioral battery for children exposed to neurotoxic chemicals. Neurotoxicology 22: pp. 657-665 CrossRef
11. Absalon, D, Slesak, B (2010) The effects of changes in cadmium and lead air pollution on cancer incidence in children. Sci Total Environ 408: pp. 4420-4428 CrossRef
12. Canfield, RL, Henderson, CR, Cory-Slechta, DA, Cox, C, Jusko, TA, Lanphear, BP (2003) Intellectual impairment in children with blood lead concentrations below 10 μg per deciliter. N Engl J Med 348: pp. 1517-1526 CrossRef
13. Mendelsohn, AL, Dreyer, BP, Fierman, AH, Rosen, CM, Legano, LA, Kruger, HA, Lim, SW, Barasch, S, Au, L, Courtlandt, CD (1999) Low-level lead exposure and cognitive development in early childhood. J Dev Behav Pediatr 20: pp. 425-431 CrossRef
14. Jarup, L (2003) Hazards of heavy metal contamination. Br Med Bull 68: pp. 167-182 CrossRef
15. Stathopoulou, MG, Kanoni, S, Papanikolaou, G, Antonopoulou, S, Nomikos, T, Dedoussis, G (2012) Mineral intake. Prog Mol Biol Transl Sci 108: pp. 201-236 CrossRef
16. Parsons, PJ, Barbosa, F (2007) Atomic spectrometry and trends in clinical laboratory medicine. Spectrochim Acta Atom Spectrosc 62: pp. 992-1003- 刊物主题：Biochemistry, general; Biotechnology; Nutrition; Oncology;
- 出版者：Springer US
- ISSN：1559-0720
文摘
The aim of this study was to investigate the relationship of blood lead (Pb) levels with copper (Cu), zinc (Zn), calcium (Ca), magnesium (Mg), iron (Fe), and hemoglobin (Hb) in children aged from 0-?years in Wuhan, China. A total of 1047 children from six communities, which were randomly selected in Wuhan city and three communities, located in the urban area and others in the suburban area, were recruited for this study between November 2012 and July 2013. The levels of elements in the blood were detected using an atomic absorption spectrometer, and Hb level was tested by an automated hematology analyzer. The results showed that the mean blood lead level (BLL) is 33.72?±-9.03?μg/L. The BLL was significantly higher among boys than girls (P--.05). Higher BLL was also observed in suburbs compared to that in urban areas (P--.05). The BLL and Zn level were gradually increased with age. The elevated rate of BLL in children was 20.9?%, while the Zn deficiency rate was 65.0?%. And, the level of Hb in higher BLL group was significantly lower. Negative correlations of the blood levels of Pb with those of Cu (r-??0.087, P--.005), Mg (r-??0.102, P--.001), and Fe (r-??0.091, P--.003) were observed. These data suggested that the elevated rate of BLL in children from Wuhan is still higher according to the updated reference values in the USA. The deficiency of Cu, Mg, and Fe may indicate the elevation of lead absorption. The dietary supplement of Zn, Ca, and Fe in children requires more attention.