Monoclonal antibodies for human and porcine histamine N-methyltransferase (HMT) facilitate protein expression and localization studies

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• 作者：Hubert G. Schwelberger ; Johannes Feurle ; Gunnar Houen
• 关键词：Histamine N ; methyltransferase ; Histamine metabolism ; Monoclonal antibodies ; Protein expression ; Protein localization
• 刊名：Inflammation Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：66
• 期：1
• 页码：67-77
• 全文大小：1904KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Immunology; Pharmacology/Toxicology; Rheumatology; Allergology; Dermatology; Neurology;
• 出版者：Springer International Publishing
• ISSN：1420-908X
• 卷排序：66

文摘

ObjectiveThe lack of suitable antibodies for the histamine inactivating enzyme histamine N-methyltransferase (HMT) has so far prevented the direct analysis of HMT proteins in man and other mammals.