HER2 testing in paired biopsy and excision specimens of gastric cancer: the reliability of the scoring system and the clinicopathological factors relevant to discordance
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作者单位:Shih-Chiang Huang (1) Kwai-Fong Ng (1) Shang-En Lee (2) Kuang-Hua Chen (1) Ta-Sen Yeh (3) Tse-Ching Chen (1) (4)
1. Department of Anatomical Pathology, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan, ROC 2. Cancer Diagnostic Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC 3. Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan, ROC 4. Department of Pathology, Chang Gung Memorial Hospital, No. 5 Fuxing St., Guishan Township, Taoyuan County, 333, Taiwan, ROC
刊物类别:Medicine
刊物主题:Medicine & Public Health Oncology Gastroenterology Surgical Oncology Pathology Radiotherapy
出版者:Springer Japan
ISSN:1436-3305
文摘
Background Inclusion of trastuzumab in chemotherapy regimens is advantageous for patients with advanced or metastatic gastric cancer who overexpress HER2. Therefore, accurate assessment of HER2 status in tumor tissue is critical when weighing treatment options.