Circulating Progenitor Cells and Childhood Cardiovascular Disease

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• 作者：Eric J. Kort ; Lacey Croskey ; Taryn Scibienski ; Surender Rajasekaran…
• 关键词：Congenital heart disease ; Stem cells ; Cardiopulmonary bypass ; Progenitor cells
• 刊名：Pediatric Cardiology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：37
• 期：2
• 页码：225-231
• 全文大小：403 KB
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• 作者单位：Eric J. Kort (1) (2) (3)
  Lacey Croskey (2)
  Taryn Scibienski (2)
  Surender Rajasekaran (2) (3)
  Stefan Jovinge (1) (2) (4)
  
  1. DeVos Cardiovascular Research Program of Spectrum Health and Van Andel Research Institute, 100 Michigan Street NE, Grand Rapids, MI, 49503, USA
  2. Michigan State University, College of Human Medicine, 15 Michigan Street NE, Grand Rapids, MI, USA
  3. Helen DeVos Children’s Hospital, 100 Michigan Street NE, Grand Rapids, MI, USA
  4. Cardiovascular Institute, Stanford University, Palo Alto, CA, USA
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Cardiology
  Cardiac Surgery
  Vascular Surgery
  
• 出版者：Springer New York
• ISSN：1432-1971

文摘

Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowledge pertaining to circulating progenitor cells in the context of childhood cardiovascular disease. Priorities for further research are also highlighted.