Effect of pioglitazone on transdifferentiation of preosteoblasts from rat bone mesenchymal stem cells into adipocytes
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- 作者：Linfang Wang (1)
Lihua Li (2)
Haibo Gao (2)
Yuming Li (2) - 关键词：osteogenesis ; adipogenesis ; pioglitazone ; bone metabolism
- 刊名：Journal of Huazhong University of Science and Technology [Medical Sciences]
- 出版年：2012
- 出版时间：August 2012
- 年：2012
- 卷：32
- 期：4
- 页码：530-533
- 全文大小：747KB
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8. Sorocéanu MA, Miao D, Bai XY, / et al. Rosiglitazone impacts negatively on bone by promoting osteoblast/ost-eocyte apoptosis. J Endocrinol, 2004,183(1):203-16 CrossRef
9. Benvenuti S, Cellai I, Luciani P, / et al. Rosiglitazone stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells. J Endocrinol Invest, 2007,30(9):26-0
10. Moerman EJ, Teng K, Lipschitz DA, / et al. Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-γ2 transcription factor and TGF-β/BMP signaling pathways. Aging Cell, 2004,3(6):379-89 CrossRef
11. Lin TH, Yang RS, Tang CH, / et al. PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. Bone, 2007,41(4):562-74 CrossRef - 作者单位：Linfang Wang (1)
Lihua Li (2)
Haibo Gao (2)
Yuming Li (2)
1. Department of Anorectal Surgery, Huazhong University of Science and Technology, Wuhan, 430022, China
2. Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
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