La m class="a-plus-plus">Non Alcoholic Fatty Liver Diseasem> (NAFLD) et la m class="a-plus-plus">Non Alcoholic Steato-Hepatitism> (NASH) des pathologies de système : revue pour le réanimateur

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• 作者：M. Hachemi ; S. Benmakhlouf ; P. Prost ; N. Santolaria…
• 关键词：Mots clésNon Alcoholic Fatty Liver Disease (NAFLD) ; Non Alcoholic Steato ; Hepatitis (NASH) ; Syndrome métabolique ; Insulinorésistance ; Obésité ; Épidémiologie ; Elafibranor
• 刊名：Médecine Intensive Réanimation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：26
• 期：1
• 页码：63-74
• 全文大小：
• 刊物主题：Emergency Medicine; Anesthesiology; Intensive / Critical Care Medicine;
• 出版者：Lavoisier
• ISSN：1951-6959
• 卷排序：26

文摘

NAFLD and NASH are multisystemic disease linked to metabolic syndrom, insulin resistance and obesity. Cardiovascular abnormalities are common in NAFLD and are the principal cause of mortality in the disease, follow by neoplasia and liver complications. The biopharmaceutical research is developping new target in NASH with the aim of reversion NASH without worsening fibrosis. NAFLD is the most common cause of chronic liver disease in Western countries and should be the first indication for liver transplantation in near years in USA. NAFLD presents as such a major interest for the physician intensivist.