Changes in short-term health-related quality of life in women undergoing gynecologic oncologic laparotomy: an associated factor analysis

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• 作者：Lucas Minig (1) (2)
  Jorge Iván Vélez (4)
  Edward L. Trimble (3)
  Roberto Biffi (5)
  Angelo Maggioni (1)
  Diana D. Jeffery (6)
  
• 关键词：Quality of life ; Gynecologic cancer ; Laparotomy
• 刊名：Supportive Care in Cancer
• 出版年：2013
• 出版时间：March 2013
• 年：2013
• 卷：21
• 期：3
• 页码：715-726
• 全文大小：231KB
• 参考文献：1. http://www.cancer.gov/. Accessed 20 February 2012
  2. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed 20 February 2012
  3. Matsushita T, Murata H, Matsushima E et al (2007) Emotional state and coping style among gynecologic patients undergoing surgery. Psychiatry Clin Neurosci 61:84-3 CrossRef
  4. Cella DF, Bonomi AE (1998) Measuring quality of life. In: Pazdur R, Coia LR, Hoskins WJ et al (eds) Cancer management: a multidisciplinary approach, 2nd edn. PRR Inc, Huntington, pp 807-14
  5. Carlsson M, Strang P, Bjurstrom C (2000) Treatment modality affects long-term quality of life in gynaecological cancer. Anticancer Res 20:563-68
  6. Kornblith AB, Thaler HT, Wong G et al (1995) Quality of life of women with ovarian cancer. Gynecol Oncol 59:231-42 CrossRef
  7. Minig L, Biffi R, Zanagnolo V et al (2009) Early oral versus “traditional-postoperative feeding in gynecologic oncology patients undergoing intestinal resection: a randomized controlled trial. Ann Surg Oncol 16:1660-668 CrossRef
  8. Minig L, Biffi R, Zanagnolo V et al (2009) Reduction of postoperative complication rate with the use of early oral feeding in gynaecologic oncologic patients undergoing a major surgery: a randomized controlled trial. Ann Surg Oncol 16:3101-110 CrossRef
  9. Aletti GD, Santillan A, Eisenhauer E et al (2007) A new frontier for quality of care in gynecologic oncology surgery: multi-institutional assessment of short-term outcomes for ovarian cancer using a risk-adjusted model. Gynecol Oncol 107:99-06 CrossRef
  10. Benedet JL, Bender H, Jones H 3rd et al (2000) FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet 70:209-62 CrossRef
  11. Aaronson NK, Ahmedzai S, Bergman B et al (1993) The European Organization for Research and Treatment of Cancer HR-QOL C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85:365-67 CrossRef
  12. Greimel E, Bottomley A, Cull A et al (2003) An international field study of the reliability and validity of a disease-specific questionnaire module (the QLQ-OV28) in assessing the quality of life of patients with ovarian cancer. Eur J Cancer 39:1402-408 CrossRef
  13. http://groups.eortc.be/qol/documentation_manuals.htm. Accessed 20 February 2012
  14. Greimel E, Thiel I, Peintinger F et al (2002) Prospective assessment of quality of life of female cancer patients. Gynecol Oncol 85:140-47 CrossRef
  15. von Gruenigen V, Gil K, Frasure H et al (2005) The impact of obesity and age on quality of life in gynecologic surgery. Am J Obstet Gynecol 193:1369-375 CrossRef
  16. Eisemann M, Lalos A (1999) Psychosocial determinants of wellbeing in gynecologic cancer patients. Cancer Nurs 22:303-06 CrossRef
  17. Basen-Engquist K, Bodurka-Bevers D, Fitzgerald MA et al (2001) Reliability and validity of the functional assessment of cancer therapy-ovarian. J Clin Oncol 19:1809-817
  18. Bhattacharya SM, Jha A (2010) A comparison of Health-Related Quality of Life (HRQOL) after natural and surgical menopause. Maturitas 66:431-34 CrossRef
  19. Teplin V, Vittinghoff E, Lin F, Learman L et al (2007) Oophorectomy in premenopausal women health-related quality of life and sexual functioning. Obstet Gynecol 109:347-54 CrossRef
  20. Vernooij F, Heintz P, Witteveen E et al (2007) The outcomes of ovarian cancer treatment are better when provided by gynecologic oncologists and in specialized hospitals: a systematic review. Gynecol Oncol 105:801-12 CrossRef
  21. Chan YM, Ngan HYS, Li BYG et al (2001) A longitudinal study on quality of life after gynecologic cancer treatment. Gynecol Oncol 83:10-9
  22. Eisemann M, Lalos A (1999) Psychosocial determinants of wellbeing in gynecologic cancer patients. Cancer Nurs 22:303-06
  
• 作者单位：Lucas Minig (1) (2)
  Jorge Iván Vélez (4)
  Edward L. Trimble (3)
  Roberto Biffi (5)
  Angelo Maggioni (1)
  Diana D. Jeffery (6)
  
  1. Gynecology Department, European Institute of Oncology, Milan, Italy
  2. Gynecology Oncology Program, Hospital Universitario Madrid Sanchinarro, Centro Integral Oncológico Clara Campal (CIOCC), Calle O?a 10, 28050, Madrid, Spain
  4. Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
  3. Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
  5. Abdomino-Pelvic Surgery Department, European Institute of Oncology, Milan, Italy
  6. Office of the Assistant Secretary of Defence (Health Affairs), TRICARE Management Activity, Health Program Analysis and Evaluation, Department of Defense, Falls Church, VA, 22041-3206, USA
  
• ISSN：1433-7339

文摘

Purpose The primary purpose of this study is to evaluate health-related quality of life (HR-QOL) of gynecologic cancer patients undergoing laparotomy. Methods Women who underwent laparotomy by gynecologic cancer completed the European Organization for Research and Treatment of Cancer (EORTC) Quality of life questionnaires (QLQ‐C30 and QLQ‐OV28) presurgery and at 1 month. Results Of the 181 women studied between January 2007 and March 2008, 116 women (64.1?%) had ovarian cancer, 27 (14.9?%) had cervical cancer, and 29 (16.0?%) had endometrial cancer. By 1?month post-surgery, there was a significant decrease in HR-QOL on the global, abdominal/gastrointestinal (GI) score, body image, chemotherapy side effects, and other single items of the OV28 questionnaire, as well as on physical, role and social functioning, fatigue, nausea and vomiting, pain, insomnia, constipation, appetite loss, and financial difficulties items on C30 questionnaires. Emotional functioning on C30 questionnaires was significantly improved 1?month after surgery. The majority of these items persisted 1?month after surgery only in patients with ovarian cancer. Abdominal/GI score on OV28 questionnaires as well as role and physical functioning on C30 questionnaires were significantly lower between baseline and postsurgical HR-QOL in women with other gynecologic malignancies. Conclusion The results suggest a significant impact of HR-QOL among gynecologic cancer patients 1?month after laparotomy, particularly among those with ovarian cancer.