Early aggressive macrovascular disease and type 1 diabetes mellitus without chronic complications: a case report

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• 作者：Alessandra Saldanha de Mattos Matheus (4)
  Marília Brito Gomes (4)
  
• 关键词：Diabetes mellitus ; Type 1 ; Coronary artery disease ; Macrovascular complications ; Cardiovascular risk
• 刊名：BMC Research Notes
• 出版年：2013
• 出版时间：December 2013
• 年：2013
• 卷：6
• 期：1
• 全文大小：601KB
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• 作者单位：Alessandra Saldanha de Mattos Matheus (4)
  Marília Brito Gomes (4)
  
  4. Diabetes Unit, State University of Rio de Janeiro, Rio de Janeiro, Brazil
  

文摘

Background Type 1 diabetes (T1DM) is considered to be one of the most significant risk factors for the development of coronary artery disease (CAD). However, the specific risk predictor models for T1DM are subject to many limitations. Case presentation We report the case of a 42-year-old Caucasian woman presenting with T1DM for 26?years. During her chronic hyperglycemic evolution (mean of HbA1c-gt;- percentage points above the superior limit) without microvascular complications, this patient presented with early and aggressive coronary artery disease, despite the lack of classical risk factors for CAD Conclusions The rapidly progressive macrovascular disease observed in this case demonstrates the different degrees of aggressiveness and unpredictable clinical evolution observed in some cases. It also confirms the need for a multi-factorial, early and optimized clinical management regime.