Maximal oxygen uptake and exercise tolerance are improved in rats with heart failure subjected to low-level laser therapy associated with resistance training

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• 作者：Vítor Scotta Hentschke ; Lucas Capalonga…
• 关键词：Myocardial infarction ; Phototherapy ; Maximal exercise test ; Functional capacity ; Echocardiography
• 刊名：Lasers in Medical Science
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：32
• 期：1
• 页码：73-85
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Medicine/Public Health, general; Dentistry; Optics, Lasers, Photonics, Optical Devices; Quantum Optics;
• 出版者：Springer London
• ISSN：1435-604X
• 卷排序：32

文摘

Exercise tolerance and maximal oxygen uptake (VO_2max) are reduced in heart failure (HF). The influence of combined resistance training (RT) and low-level laser therapy (LLLT) on exercise tolerance and VO_2max in HF has not yet been explored. The aim of this study was to evaluate the influence of combined RT and LLLT on VO_2max and exercise tolerance in rats with HF induced by myocardial infarction (MI). Rats were allocated to sedentary sham (Sed-Sham, n = 12), sedentary heart failure (Sed-HF, n = 9), RT heart failure (RT-HF, n = 7) and RT associated with LLLT heart failure (RT + LLLT-HF, n = 7) groups. After MI or sham surgery, rats underwent a RT and LLLT protocol (applied immediately after RT) for 8 weeks. VO_2max and exercise tolerance were evaluated at the end of protocol. HF rats subjected to LLLT combined with RT showed higher VO_2basal (41 %), VO_2max (40 %), VO_2reserve (39 %), run distance (46 %), time to exhaustion (30 %) and maximal velocity (22 %) compared with HF rats that underwent RT alone. LLLT associated with RT improved oxygen uptake and exercise tolerance compared with RT alone in HF rats.