Energy Adaptations Persist 2 Years After Sleeve Gastrectomy and Gastric Bypass

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• 作者：Charmaine S. Tam ; Georgia Rigas ; Leonie K. Heilbronn ; Tania Matisan…
• 关键词：Energy expenditure ; Resting metabolic rate ; Metabolic adaptation
• 刊名：Obesity Surgery
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：26
• 期：2
• 页码：459-463
• 全文大小：322 KB
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• 作者单位：Charmaine S. Tam (1)
  Georgia Rigas (2)
  Leonie K. Heilbronn (3)
  Tania Matisan (2)
  Yasmine Probst (4)
  Michael Talbot (2)
  
  1. The Charles Perkins Centre and School of Biological Sciences, University of Sydney, Sydney, Australia
  2. Upper Gastrointestinal Unit, Department of Surgery, St George Private Hospital, Suite 3, Level 5, 1 South St, Kogarah, Australia
  3. Discipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia
  4. Smart Foods Centre, School of Medicine, University of Wollongong, Wollongong, NSW, Australia
  
• 刊物主题：Surgery;
• 出版者：Springer US
• ISSN：1708-0428

文摘

Non-surgical weight loss induces a greater than expected decrease in energy expenditure, a phenomenon known as ‘metabolic adaptation’. The effects of different bariatric surgery procedures on metabolic adaptation are not yet known and may partially contribute to weight loss success. We compared resting energy expenditure (REE) in 35 subjects (nine males; age = 46 ± 11 years; BMI = 42.1 ± 6.5 kg/m2) undergoing gastric band, sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) up to 2 years after surgery. We found a greater than expected reduction of 130–300 kcal/day at 6 weeks after sleeve and bypass surgery which was not explained by changes in body composition; this change was not seen in the band group. The suppression in REE after sleeve and RYGB remained up to 2 years, even after weight loss had plateaued. Our findings suggest that energy adaptation is not a contributing mechanism to medium-term weight maintenance after sleeve and RYGB bariatric surgeries. Keywords Energy expenditure Resting metabolic rate Metabolic adaptation