Regulation of a disintegrins and metalloproteinase with thrombospondin motifs 7 during inflammation in nucleus pulposus (NP) cells: role of AP-1, Sp1 and NF-κB signaling
刊物主题:Biomedicine Immunology Pharmacology and Toxicology Allergology Dermatology Neurology Rheumatology
出版者:Birkh盲user Basel
ISSN:1420-908X
卷排序:65
文摘
AimThe objective of this study is to explore the effect of inflammatory cytokines on a disintegrins and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) and to demonstrate the role of Sp1, AP-1 and NF-κB signaling on the ADAMTS7 regulation during inflammation in NP cells.