Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes
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- 作者：Zabeen Lateef ; Gregory Gimenez ; Estelle S. Baker ; Vernon K. Ward
- 关键词：Human norovirus (HuNoV) ; NS1 ; 2 ; Disordered protein ; Murine norovirus (MNV) ; RNAseq ; Transcriptomic analysis
- 刊名：BMC Genomics
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：5927KB
- 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
- 出版者：BioMed Central
- ISSN：1471-2164
- 卷排序：18
文摘
BackgroundThe GII.4 Sydney 2012 strain of human norovirus (HuNoV) is a pandemic strain that is responsible for the majority of norovirus outbreaks in healthcare settings. The function of the non-structural (NS)1-2 protein from HuNoV is unknown.