Narcolepsy with Cataplexy in an Elderly Woman

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• 作者：Shingo Suzuki MD ; PhD ; Takanori Uehara MD ; PhD…
• 关键词：cataplexy ; narcolepsy ; orexin/hypocretin ; video ; elderly
• 刊名：Journal of General Internal Medicine
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：30
• 期：8
• 页码：1222-1224
• 全文大小：121 KB
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• 作者单位：Shingo Suzuki MD, PhD (1)
  Takanori Uehara MD, PhD (1)
  Yoshiyuki Ohira MD, PhD (1)
  Masatomi Ikusaka MD, PhD (1)
  
  1. Department of General Medicine, Chiba University Hospital, 1-8-1, Inohana, Chuo-ku, Chiba-city, Chiba, 260-8677, Japan
  
• 刊物主题：Internal Medicine;
• 出版者：Springer US
• ISSN：1525-1497

文摘

A 72-year-old woman was referred for a 15-year history of brief attacks of generalized weakness that occurred when she was tense or startled. During these episodes, she squatted, closed her eyes, and had difficulty speaking, but there was no disturbance of consciousness. The cerebrospinal fluid level of orexin/hypocretin was low (92?ng/L), leading to a diagnosis of narcolepsy with cataplexy according to the International Classification of Sleep Disorders (ICSD)-2 criteria. Cataplexy should be considered for sudden attacks of weakness lasting less than 2 minutes and with no alteration of consciousness. Measurement of cerebrospinal fluid levels of orexin/hypocretin is recommended when the diagnosis is uncertain.