Molecular characterization of Nipah virus from Pteropus hypomelanus in Southern Thailand
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- 作者：Supaporn Wacharapluesadee ; Panumas Samseeneam ; Mana Phermpool…
- 关键词：Nipah virus ; Bats ; Strain ; Transmission ; Southern ; Thailand
- 刊名：Virology Journal
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：13
- 期：1
- 全文大小：1,294 KB
- 刊物主题：Virology;
- 出版者：BioMed Central
- ISSN：1743-422X
文摘
Background Nipah virus (NiV) first emerged in Malaysia in 1998, with two bat species (Pteropus hypomelanus and P. vampyrus) as the putative natural reservoirs. In 2002, NiV IgG antibodies were detected in these species from Thailand, but viral RNA could not be detected for strain characterization. Two strains of NiV (Malaysia and Bangladesh) have been found in P. lylei in central Thailand, although Bangladesh strain, the causative strain for the outbreak in Bangladesh since 2001, was dominant. To understand the diversity of NiV in Thailand, this study identified NiV strain, using molecular characterizations, from P. hypomelanus in southern Thailand.