参考文献:1.Adams SL, Cohen AJ, Lassová L (2007) Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation. J Cell Physiol 213:635–641CrossRef PubMed 2.Federative Committee on Anatomical Terminology (FCAT) (1998) Terminologia anatomica: international anatomical terminology. Georg Thieme Verlag, Stuttgart 3.Hurley JM, Betz RR, Loder RT, Davidson RS, Alburger PD, Steel HH (1996) Slipped capital femoral epiphysis. The prevalence of late contralateral slip. J Bone Joint Surg Am 78:226–230PubMed 4.Milz S, Boszczyk A, Putz R (2002) Entwicklung und Funktion der Epiphysenfuge. Orthopäde 31:835–840CrossRef PubMed 5.Milz S, Putz R, Benjamin M (2005) Molecular parameters indicating adaptation to mechanical stress in fibrous connective tissue. Adv Anat Histol Embryol Cell Biol 178:1–71CrossRef 6.Moore KL, Persaud TVN, Torchia MG, Viebahn C (2013) Embryologie, 6. Aufl. Elsevier, München 7.Morscher E (1961) Die mechanischen Verhältnisse des Hüftgelenkes und ihre Beziehungen zum Halsschaftwinkel und insbesondere zur Antetorsion des Schenkelhalses während der Entwicklungsjahre. Z Orthop 94:374–394PubMed 8.Morrison EH, Ferguson MW, Bayliss MT, Archer CW (1996) The development of articular cartilage: I. The spatial and temporal patterns of collagen types. J Anat 189:9–22PubMed PubMedCentral 9.Olsen BR (1995) Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias. Bone 17(2 Suppl):45S–49SCrossRef PubMed 10.Pauwels F (1960) Eine neue Theorie über den Einfluß mechanischer Reize auf die Differenzierung der Stützgewebe. X. Beitrag zur funktionellen Anatomie und kausalen Morphologie des Stützgewebes. Z Anat EntwicklGesch 117:478–515CrossRef 11.Putz R (1996) Entwicklung und Wachstum der Epiphysen. Z Orthop 134:391–395CrossRef PubMed 12.Ranvier L (1873) Quelque faits relatifs au développement du tissus osseux. C R Acad Sci 77:1105–1109 13.Reinecke M, Schmid AC, Heyberger-Meyer B, Hunziker EB, Zapf J (2000) Effect of growth hormone and insulin-like factor I (IGF-I) on the expression of IGF-I messenger ribonucleic acid and peptide in rat tibial growth plate and articular chondrocytes in vivo. Endocrinology 141:2847–2853PubMed 14.Skuban TP, Vogel T, Baur-Melnyk A, Jansson V, Heimkes B (2009) Function-orientated structural analysis of the proximal human femur. Cells Tissues Organs (Print) 190:247–255CrossRef 15.Putz R, Pabst R (Hrsg) (2010) Sobotta – Atlas der Anatomie des Menschen, 22. Aufl. Elsevier, München 16.Tillmann B (1996) Struktur und Funktion der Wachstumsplatte. Z Orthop 134:396–399CrossRef PubMed 17.Wirtz A (1920) Periostale Ossifikation. Archiv für orthopädische und Unfall-Chirurgie, mit besonderer Berücksichtigung der Frakturenlehre und der orthopädisch-chirurgischen Technik 18:559–575CrossRef
作者单位:Prof. Dr. Dr. h.c. R. Putz (1) S. Milz (1)
1. Anatomische Anstalt, Ludwig-Maximilians-Universität München, Pettenkoferstraße 11, 80336, München, Deutschland
Apophyses are growth zones attached to the shaft (corpus) of larger bones. They vary in size and develop their own ossification centres or form as part of an usually fibrocartilaginous tendon or ligament insertion. The structure of the cartilaginous apophyseal plate is very similar to that of an epiphyseal growth plate and like these they are adapted to withstand perpendicular compressive forces without becoming harmed. This is best highlighted by the fact that their mineralized borders always orient themselves perpendicular to the overall resulting force vector. The edges of the apophyseal plates are characteristically bent which allows them to resist moderate shear forces. Like the epiphyseal plates the apophyseal plates exhibit a zonal organization which is not very well adapted to permanently withstand shear forces, especially if they occur under dynamic conditions. In these situations the tendinous insertions with their collagen fibre anchoring system have to provide compensation when balancing the load transmitted across the system.