Oscillating bubbles in teardrop cavities for microflow control

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• 作者：Ali Hashmi (1)
  Garrett Heiman (1)
  Gan Yu (1)
  Mark Lewis (1)
  Hyuck-Jin Kwon (1)
  Jie Xu (1)
  
• 关键词：Teardrop cavities ; Microfluidics ; Oscillating bubbles ; Microflow ; Acoustic actuation
• 刊名：Microfluidics and Nanofluidics
• 出版年：2013
• 出版时间：4 - March 2013
• 年：2013
• 卷：14
• 期：3
• 页码：591-596
• 全文大小：356KB
• 参考文献：1. Ahmed D, Mao XL, Juluri BK, Huang TJ (2009a) A fast microfluidic mixer based on acoustically driven sidewall-trapped microbubbles. Microfluid Nanofluid 7(5):727鈥?31 CrossRef
  2. Ahmed D, Mao XL, Shi JJ, Juluri BK, Huang TJ (2009b) A millisecond micromixer via single-bubble-based acoustic streaming. Lab Chip 9(18):2738鈥?741 CrossRef
  3. Betz A, Xu J, Qiu H, Attinger D (2010) Do surfaces with mixed hydrophilic and hydrophobic areas enhance pool boiling? Appl Phys Lett 97:141909 CrossRef
  4. Chung SK, Cho SK (2008) On-chip manipulation of objects using mobile oscillating bubbles. J Micromech Microeng 18:12
  5. Chung SK, Cho SK (2009) 3-D manipulation of millimeter- and micro-sized objects using an acoustically excited oscillating bubble. Microfluid Nanofluid 6(2):261鈥?65 CrossRef
  6. Drelich J, Chibowski E, Meng DD, Terpilowski K (2011) Hydrophilic and superhydrophilic surfaces and materials. Soft Matter 7(21):9804 CrossRef
  7. Elder SA (1959) Cavitation microstreaming. J Acoust Soc Am 31(1):11 CrossRef
  8. Garty G, Grad M, Jones BK, Xu Y, Xu J, Randers-Pehrson G, Attinger D, Brenner DJ (2011) Design of a novel flow-and-shoot microbeam. Radiat Prot Dosim 143(2鈥?):344鈥?48 CrossRef
  9. Hashmi A, Yu G, Reilly-Collette M, Heiman G, Xu J (2012a) Oscillating bubbles: a versatile tool for lab on a chip applications. Lab Chip 12(21):4216鈥?227 CrossRef
  10. Hashmi A, Yu G, Xu Y, Kwon HJ, Chen XL, Xu J (2012b) Microbubble array for on-chip worm processing (submitted)
  11. Hettiarachchi K, Lee AP (2010) Polymer鈥搇ipid microbubbles for biosensing and the formation of porous structures. J Colloid Interf Sci 344(2):521鈥?27 CrossRef
  12. Hettiarachchi K, Zhang S, Feingold S, Lee AP, Dayton PA (2009) Controllable microfluidic synthesis of multiphase drug-carrying lipospheres for site-targeted therapy. Biotechnol Prog 25(4):938鈥?45 CrossRef
  13. Huang PH, Lapsley MI, Ahmed D, Chen Y, Wang L, Huang TJ (2012) A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles. Appl Phys Lett 101(14):141101 CrossRef
  14. Kao J, Wang XL, Warren J, Xu J, Attinger D (2007) A bubble-powered micro-rotor: conception, manufacturing, assembly and characterization. J Micromech Microeng 17(12):2454鈥?460 CrossRef
  15. Kwon JO, Yang JS, Lee SJ, Rhee K, Chung SK (2011) Electromagnetically actuated micromanipulator using an acoustically oscillating bubble. J Micromech Microeng 21:11
  16. Lee KH, Lee JH, Won JM, Rhee K, Chung SK (2011) Micromanipulation using cavitational microstreaming generated by acoustically oscillating twin bubbles. Sensor Actuat A Phys. doi:10.1016/j.sna.2011.11.037
  17. Leslie DC, Easley CJ, Seker E, Karlinsey JM, Utz M, Begley MR, Landers JP (2009) Frequency-specific flow control in microfluidic circuits with passive elastomeric features. Nat Phys 5(3):231鈥?35 CrossRef
  18. Liu RH, Yang JN, Pindera MZ, Athavale M, Grodzinski P (2002) Bubble-induced acoustic micromixing. Lab Chip 2(3):151鈥?57 CrossRef
  19. Liu C, Thompson JA, Bau HH (2011) A membrane-based, high-efficiency, microfluidic debubbler. Lab Chip 11(9):1688鈥?693 CrossRef
  20. Marmottant P, Hilgenfeldt S (2003) Controlled vesicle deformation and lysis by single oscillating bubbles. Nature 423(6936):153 CrossRef
  21. Marmottant P, Hilgenfeldt S (2004) A bubble-driven microfluidic transport element for bioengineering. P Natl Acad Sci USA 101(26):9523鈥?527 CrossRef
  22. Marmottant P, Raven JP, Gardeniers H, Bomer JG, Hilgenfeldt S (2006) Microfluidics with ultrasound-driven bubbles. J Fluid Mech 568:109鈥?18 CrossRef
  23. Matsumoto K, Ueno I (2009) Oscillating bubbles in ultrasonic acoustic field. J Phys Conf Ser 147:012015 CrossRef
  24. Okabe Y, Chen Y, Purohit R, Corn RM, Lee AP (2012) Piezoelectrically driven vertical cavity acoustic transducers for the convective transport and rapid detection of DNA and protein binding to DNA microarrays with SPR imaging鈥擜 parametric study. Biosens Bioelectron 35(1):37鈥?3 CrossRef
  25. Packer J, Attinger D, Ventikos Y (2008) Ultrasound-driven viscous streaming, modelled via momentum injection. Sens Transducers J 3:47鈥?8
  26. Patel MV, Tovar AR, Lee AP (2012) Lateral cavity acoustic transducer as an on-chip cell/particle microfluidic switch. Lab Chip 12(1):139鈥?45 CrossRef
  27. Rogers P, Neild A (2011) Selective particle trapping using an oscillating microbubble. Lab Chip 11(21):3710鈥?715 CrossRef
  28. Stone HA, Stroock AD, Ajdari A (2004) Engineering flows in small devices: microfluidics toward a lab-on-a-chip. Annu Rev Fluid Mech 36:381鈥?11 CrossRef
  29. Tovar A, Patel M, Lee A (2011) Lateral air cavities for microfluidic pumping with the use of acoustic energy. Microfluid Nanofluid 10(6):1269鈥?278 CrossRef
  30. Wang Z, Zhe J (2011) Recent advances in particle and droplet manipulation for lab-on-a-chip devices based on surface acoustic waves. Lab Chip 11(7):1280鈥?285 CrossRef
  31. Wang XL, Attinger D, Moraga F (2006) A micro-rotor driven by an acoustic bubble. Nanosc Microsc Therm 10(4):379鈥?85 CrossRef
  32. Wang C, Jalikop SV, Hilgenfeldt S (2011a) Size-sensitive sorting of microparticles through control of flow geometry. Appl Phys Lett 99:3
  33. Wang SS, Huang XY, Yang C (2011b) Mixing enhancement for high viscous fluids in a microfluidic chamber. Lab Chip 11(12):2081鈥?087 CrossRef
  34. Won JM, Lee JH, Lee KH, Rhee K, Chung SK (2011) Int J Precis Eng Man 12:577鈥?80 CrossRef
  35. Xie Y, Ahmed D, Lapsley MI, Lin SC, Nawaz AA, Wang L, Huang TJ (2012) Single-shot characterization of enzymatic reaction constants / k _m and / k _cat by an acoustic-driven, bubble-based fast micromixer. Anal Chem 84(17):7495鈥?501 CrossRef
  36. Xu J, Attinger D (2007a) Acoustic excitation of superharmonic capillary waves on a meniscus in a planar microgeometry. Phys Fluids 19:108107 CrossRef
  37. Xu J, Attinger D (2007b) Control and ultrasonic actuation of a gas-liquid interface in a microfluidic chip. J Micromech Microeng 17(3):609鈥?16 CrossRef
  38. Xu J, Attinger D (2008) Drop on demand in a microfluidic chip. J Micromech Microeng 18:065020 CrossRef
  39. Xu J, Vaillant R, Attinger D (2010) Use of a porous membrane for gas bubble removal in microfluidic channels: physical mechanisms and design criteria. Microfluid Nanofluid 9(4):765鈥?72 CrossRef
  40. Yu G, Chen XL, Xu J (2011) Acoustophoresis in variously shaped liquid droplets. Soft Matter 7(21):10063鈥?0069 CrossRef
  
• 作者单位：Ali Hashmi (1)
  Garrett Heiman (1)
  Gan Yu (1)
  Mark Lewis (1)
  Hyuck-Jin Kwon (1)
  Jie Xu (1)
  
  1. Department of Mechanical Engineering, Washington State University, Vancouver, WA, 98686, USA
  
• ISSN：1613-4990

文摘

Microstreaming generated from oscillating microbubbles has great potential in microfluidic applications for localized flow control. In this study, we explore the use of teardrop-shaped cavities for trapping microbubbles. Upon acoustic actuation, these microbubbles confined in teardrop cavities can be utilized to generate a directional microstreaming flow. We further show that by altering the acoustic excitation frequency, a flow-switch for altering flow direction in microfluidic environments can be achieved using two oppositely arranged teardrop cavities with different sizes. In the end, we show that an array of such bubble-filled teardrop cavities can act as a fixated microfluidic transport system allowing for on-chip particle manipulation in complex flow patterns. This inexpensive method to create flows to switch and transport elements based on teardrop cavities can be widely employed for microfluidic applications such as drug delivery systems.